Frontal Fibrosing Alopecia: An Update on Epidemiology and Treatment

Examination of Clinical and Demographic Characteristics of 14 Cases with Frontal Fibrosing Alopecia

“…As with all our cases, symmetrical and bilateral traction on the frontal and temporal hairline of the patients is explicit. This traction increases even more over time (2,6,7). Traction on the hairline may vary, progresses slowly and spontaneously stop years after onset (6,7,20).…”

“…All our cases had cicatricial alopecia. FFA is disease of postmenopausal women by 95%, and the mean onset age of the disease is 67 (45-82) (2,3,4). A multi-center study performed by Vano et al, is the study including the largest series with 355 patients on this subject (14).…”

“…The diagnosis is usually made on a clinical basis. Histopathological examination is supportive in diagnosis (2,5,7). While the pathogenesis is not exactly known, its everincreasing incidence in recent years indicates possible involvement of environmental factors (4).…”

“…To date, however, a complete genetic analysis has not been performed. Frequent occurrence in postmenopausal period and successful treatment with 5-alpha reductase inhibitors suggest that a hormone-induced trigger mechanism and androgenetic factors may also be responsible in pathogenesis (2,3,9).…”

“…Despite its well-known clinical presentation, clinical studies regarding its treatment are not adequate (2,6). Case reports and series were reported in local and foreign literature (10)(11)(12)(13)(14)(15)(16)(17)(18)(19).…”