“…Liposomes loaded with paramagnetic Mn(II)-or Gd(III)-based imaging reporters or superparamagnetic iron oxide particles have been investigated for many applications including passive and active tumor visualization [3][4][5][6][7], detection of myocardium infarcted areas [8], imaging of lymph nodes [9], visualization of atherosclerotic plaques [10], detection of multiple sclerosis [11], bone marrow visualization [12], detection of apoptosis [13], in vivo monitoring of temperature [14] or pH [15], and imaging of drug delivery [16,17]. In addition, liposomes loaded with paramagnetic lanthanide(III) complexes, mostly different from Gd(III), have been recently proposed as highly sensitive MRI agents acting as chemical exchange saturation transfer (CEST) probes [18][19][20][21] or as T 2 susceptibility agents [22].…”