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Cited by 68 publications
(61 citation statements)
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“…The value of the membrane water permeability of the dendrimersomes was determined relaxometrically. 55 Further details about the vesicles' preparation and characterization are available in the ESI. †…”
Section: Dendrimersome Preparationmentioning
confidence: 99%
“…The value of the membrane water permeability of the dendrimersomes was determined relaxometrically. 55 Further details about the vesicles' preparation and characterization are available in the ESI. †…”
Section: Dendrimersome Preparationmentioning
confidence: 99%
“…For this reason, the quenching requires the entrapment of high amounts of the paramagnetic probe (to reduce T intra 1 in a vesicle with a lowpermeable membrane (to elongate t intra . When the relaxivity of the entrapped agent is limited by water permeability 35 of the vesicle membrane, the release of the probe is accompanied by a relaxation rate enhancement. Besides quantifying the release efficiency in vitro, this phenomenon is the basic concept for the MRI visualization of the release in vivo.…”
Section: < Tmentioning
confidence: 99%
“…In DPPC-based liposomes, the contribution to the overall relaxivity arising from the paramagnetic centers facing the inner core of the particles is typically limited by the low water permeability of the liposome bilayer. 22 Hence, it is predicted that LIPO-L-Gd may have a higher relaxivity than LIPO-GdL; a relaxivity of r 1 = 7.3 mM −1 s −1 and 6.3 mM −1 s −1 obtained for LIPO-L-Gd and LIPO-GdL, respectively, confirmed this prediction. Furthermore, as Ca(II) ions cannot cross the liposome membrane, the Ca-responsiveness of LIPO-L-Gd should be higher, because all the "sensing" units are available for binding the earth alkaline ion.…”
Section: ■ Discussionmentioning
confidence: 75%