From hypertension to heart failure

Magyar, Klara; Gal, Roland; Riba, Ádám; Habon, Tamás; Halmosi, Róbert; Tóth, Kálmán

doi:10.5494/wjh.v5.i2.85

Cited by 8 publications

(3 citation statements)

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“…Epidemiological studies showed that cardiac damage by hypertension is one of the most important HMOD. The consequences of hypertensive heart disease (HHD) are heart failure, coronary artery disease (CAD), and arrhythmias . The Framingham study demonstrated that hypertension was the major precursor in the development of HF, shown by other epidemiological studies as well .…”

Section: Introductionmentioning

confidence: 94%

An overview of hypertension and cardiac involvement in Asia: Focus on heart failure

Soenarta

Buranakitjaroen

Chia

et al. 2020

J of Clinical Hypertension

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Cardiovascular Disease (CVD) is the leading cause of deaths worldwide, contributing to about 30% of all deaths. Half of the cases of CVD are estimated in Asia, the world's most populous continent. Hypertension, a major modifiable risk factor for and CME seminars from Abbott, Bayer, Boehringer Ingelheim, GlaxoSmithKline, Menarini, Merck Sharp & Dohme, Novartis, Orient Europharma, Pfizer, and Sanofi; and a research grant from Pfizer. J Nailes has received research grants from Pfizer. J Shin has received honoraria and sponsorship to attend seminars from Daiichi Sankyo, Takeda, Menarini, MSD, Bristol-Myers Squibb, and Sanofi. CH Chen has served as an advisor or consultant for Novartis PharmaceuticalsCorporation and has served as a speaker or a member of a speakers

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Section: Introductionmentioning

confidence: 94%

An overview of hypertension and cardiac involvement in Asia: Focus on heart failure

Soenarta

Buranakitjaroen

Chia

et al. 2020

J of Clinical Hypertension

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“…Hypertension has become a major global health problem today. It is estimated that the current prevalence of hypertension is about 30-45% in the general population and this proportion increases with age [1]. In Vietnam, the incidence of hypertension has also increased from 18.69% in 2002 to 25.1% in 2012 [2].…”

Section: Introductionmentioning

confidence: 99%

Early detecting myocardial entity damage using 2D speckle tracking echocardiography through strain parameters in hypertensive patients

Diễm

Nguyen

Đỗ

et al. 2022

Arterial Hypertension

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Background:The prevalence of hypertension in Vietnam is increasing consecutively. Hypertension is the cause of many complications in several vital systems such as the nervous system, kidney and, especially, the cardiovascular system. Recently, the 2D speckle tracking echocardiography (STE) technique helped to assess subclinical changes in cardiac function when there was an abnormal tissue function without any changes in morphology and cardiac function. The aim of the study was to evaluate the early change in left ventricular systolic function by STE technique in hypertensive patients with and without heart failure with preserved ejection fraction (HFpEF). Material and methods: In a cross-sectional observational study, STE technique was used to analyze left ventricular systolic strain in 151 hypertensive patients and 43 participants without cardiovascular disease as a control group. Subclinical left ventricular dysfunction was detected by echocardiographic strain parameters, especially global longitudinal strain (GLS). Results: GLS decreased in hypertensive patients without heart failure with preserved ejection fraction compared to the control group (-11.93 ± 2.21 vs. -16.52 ± 1.19). This reduction increased in hypertensive patients with heart failure with preserved ejection fraction (-11.04 ± 2.5 vs. -16.52 ± 1.19). The threshold of the global longitudinal strain was -14.364. The rate of reduction in GLS in hypertensive patients without HFpEF was relatively high (93.3%). Conclusion: STE technique helps to detect subclinical changes in left ventricular systolic function with high sensitivity.

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“…A meta-analysis of 61 prospective studies revealed a log-linear relationship between the increase in systolic blood pressure (SBP; from < 115 mm Hg to > 180 mm Hg) as well as diastolic blood pressure (DBP; from < 75 mm Hg to > 105 mm Hg) and increased risk of cardiovascular diseases (CVDs) (Lewington et al, 2002). Importantly, 20 mmHg elevated SBP aguments about 50% risk of heart failure (Haider et al, 2003). Since WHO designated CVDs as the predominant cause of death globally it is not surprising that hypertension is considered to be an important issue.…”

Section: Introductionmentioning

confidence: 99%

How Hypertension Affects Heart Metabolism

et al. 2019

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Hypertension is one of the most frequently observed cardiovascular diseases, which precedes heart failure in 75% of its cases. It is well-established that hypertensive patients have whole body metabolic complications such as hyperlipidemia, hyperglycemia, decreased insulin sensitivity or diabetes mellitus. Since myocardial metabolism is strictly dependent on hormonal status as well as substrate milieu, the above mentioned disturbances may affect energy generation status in the heart. Interestingly, it was found that hypertension induces a shift in substrate preference toward increased glucose utilization in cardiac muscle, prior to structural changes development. The present work reports advances in the aspect of heart metabolism under high blood pressure conditions, including human and the most common animal models of hypertension.

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From hypertension to heart failure

Cited by 8 publications

References 0 publications

An overview of hypertension and cardiac involvement in Asia: Focus on heart failure

An overview of hypertension and cardiac involvement in Asia: Focus on heart failure

Early detecting myocardial entity damage using 2D speckle tracking echocardiography through strain parameters in hypertensive patients

How Hypertension Affects Heart Metabolism

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