Fresh frozen homologous bone in oral surgery: case reports

Abstract

Intraoral bone defects may be treated using autologous grafts, homologous grafts, heterologous grafts or synthetic products. Autologous bone is now considered the gold standard for bone grafting procedures. Homologous fresh frozen bone, provided by bone banks, is frequently utilized by orthopaedic surgeons because it is considered a safe material from immunological and viral points of view. In the cases reported here, homologous bone was used to repair some osseous defects without changing the surgical protocol utilized for autologous bone procedures. The main advantages of this strategy are low morbidity, shorter surgical times, more comfort and less risk of infection for the patient as well as the greater availability of bone.

Long-Term Retrospective Evaluation of Dental Implants Placed in Resorbed Jaws Reconstructed With Appositional Fresh-Frozen Bone Allografts

“…Clinically, allografts harvested from both the hip and the femur seemed to be a predictable alternative to autogenous bone grafts when used for alveolar ridge reconstruction before implant placement. The reliability of the femoral head to repair osseous defects was pointed out in a case series by D'Aloja et al, 21 who found good osseointegration of the grafts with no signs of tissue necrosis or immunological reactions. Subsequently, the same group treated 14 patients with FFB grafts, reporting an overall success rate of 100% when implants were placed from 4 to 8 months after the reconstructive procedure.…”

Fresh-frozen human bone graft to repair defect after mandibular giant follicular cyst removal: a case report

“…Several authors are recently reporting about the use of FFB in oral and maxillofacial surgery (D'Aloja et al 2008;Carinci et al 2009). FFB showed satisfactory biological properties such as its osteoconductive and osteoinductive properties, as well as its biomechanical behavior.…”

“…The osteoinductive potential, which represents the most important characteristic of this material, has been recently demonstrated (Rodella et al 2010). Another relevant property is the absence of immunogenity: it is well known that this material in not responsible for non-self reactions (D'Aloja et al 2008). Thanks to its osteoinductive behavior, FFB can be used for filling bone defect after cyst enucleation.…”

Treatment of the Atrophic Upper Jaw: Rehabilitation of Two Complex Cases

“…However, in order to obtain the success of implant therapy, in the preliminary stages it is essential to assess and classify the amount of available bone. In fact, this evaluation is fundamental for the correct implant placement, according to the principles of modern prosthetically driven implant placement [2]. …”

“…Autologous bone is typically harvested from intraoral sources [5] as the chin, the mandibular ramous, the tuber maxilla or from extraoral sources as the iliac crest, the fibula, and even parts of the skull [6]. Other graft materials, which are used in clinical practice, are the xenograft bone substitutes, derived from a species other than human, such as bovine, the allograft bone, like autogenous bone which is derived from humans, and at last, the artificial bone, such as bioglass, hydroxyapatite, or calcium phosphate [2]. For the reconstruction of extended bone defects, autologous or homologous bone grafts are preferred, in form of blocks, in order to restore the correct vertical and/or horizontal dimensions.…”