Frequency of urinary tract infection and antibiotic sensitivity of uropathogens in patients with diabetes

Abstract

Objective:To determine the frequency of urinary tract infections and antibiotic sensitivity among patients with diabetes.Methods:This observational study was carried out in Microbiology Department of Baqai Institute of Diabetology and Endocrinology (BIDE), Baqai Medical University from April 2015 to June 2016. All patients with diabetes having symptoms of UTI attending out patients department of BIDE were analyzed. All samples received in the laboratory were processed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Antimicrobial susceptibility pattern was determined by disc diffusion method.Results:A total number of 199 urine specimens, frequency of UTI were 24 (12.06%) in male and 175 (87.94%) in female. UTIs were highly found in (age group 51-60) 70 (35.18%). Escherichia coli was the most frequent pathogen (71%), followed by Klebsiellapneumoniae (7.48%), Proteus mirabilis (1.87%), Staphylococcus aureus (9.35%), Candida (5.61%) and Candidaalbicans were (2.80%). Majority of gram negative uropathogens were shown high sensitivity towards Imipenem and Piperacillin / Tazobactam followed by Nitrofurantion, Ceftriaxone, Levofloxacin, Ofloxacine, Ciprofloxacin, Norfloxacin, Cefixime, Nalidixic acid and Cephradine. Gram positive was most sensitive to Nitrofurantionand Vancomycin followed by Piperacillin / Tazobactam, Imipenem, Cephradine, Ceftriaxone, Norfloxacin and Cefixime.Conclusion:We observed the higher frequency of UTIs in female as compared to male participants due to poor hygiene. E.coli was the most frequent pathogen responsible for UTI in patients with diabetes, followed by Staphylococcus aureus.

Biofabrication using maize protein: 3D printing using zein formulations

“…We also determined the antibacterial activity of 3D-printed zein tablets formulated with NA against suspension cultures of Staphylococcus aureus ( Figure 7B). with previous reports [62,63].…”

Prevalence Of Bacterial Urinary Tract Infection And Antimicrobial Susceptibility Patterns Among Diabetes Mellitus Patients Attending Zewditu Memorial Hospital, Addis Ababa, Ethiopia

“…This rate is comparable to the rates reported from other studies in Ethiopia (Debre Tabor (10.9%) [20], Hawassa 13.8% [35], Addis Ababa 10.9% [36]), India 12.2% [18] and Romania (10.7%) [37]. However, much higher prevalence rates were reported from Bahir Dar (30.5%) [38], and Arbaminch (33.8%) [39] in Ethiopia, Sudan (19.5%) [40], India (22%) [21], Pakistan (52.76%) (41)], Egypt (52.2%) [19], and Nepal (54.25%) [42]. Inclusion of asymptomatic DM patients and exclusion of catheterized DM patients, which is a known determinant factor that may increase the prevalence of UTI [19,42], could be reasons for detecting lower prevalence of UTI in our study compared to the latter reports.…”

Antibiotic Sensitivity Pattern of Bacterial Isolates among Diabetic Outpatients with Urinary Tract Infection in Pontianak

“…Studies have shown an increasing trend in ampicillinresistance (Aamodt et al 2015;Richey et al 2015). Contradict to other studies, Nitrofurantoin showed the second rank of the highest antibiotic resistance (92.31%) (Gardiner et al 2019;Zubair and Shah 2019). Table 2 showed majority isolates have resistant to 5 antibiotics (30.76%) and 2 isolates demonstrated resistant to 9 antibiotics (15.38%).…”