Frequency of Rotavirus and Adenovirus Gastroenteritis Among Children in Shiraz, Iran

Abstract

BackgroundViral pathogens are the main cause of acute gastroenteritis in developed and developing countries. Rotavirus and adenovirus are the two important agents associated with hospitalization for diarrhea especially in children. Limitation and control of diarrhea as a costly disease must be considered in national health programs.ObjectivesEpidemiological studies on viral diarrhea and collecting data for rotavirus and adenovirus prevalence, as two important viral agents of gastroenteritis, are valuable for planning of a prospective program.Materials and Methods827 stool samples of pediatrics patients with gastroenteritis who were admitted to Dastgheib Hospital, Shiraz, Iran, from September 2008 to February 2010 were tested for presence of rotavirus and adenovirus using the EIA method. A demographic and clinical study was performed to determine the relationship between viral infection and clinical outcomes of patients.ResultsRotavirus was identified in 347 patients out of 827 (42%), adenovirus was detected in 76 (9%) of samples and 34 (4%) of patients had rotavirus-adenovirus co-infection. Diarrhea was the most common symptom in viral infected patients.ConclusionsGiven the non-specific symptoms of these viruses and the high prevalence of viral diarrhea in our region, more laboratories should be equipped for virus detection and vaccination might be considered as a prevention strategy.

Detection and Genotyping of Viral Gastroenteritis in Hospitalized Children Below Five Years Old in Cairo, Egypt

“…Most positive rotavirus (29 cases) samples and all positive enteric adenovirus (eight cases) were found in children below two years old. These findings are consistent with previous research, in which the majority of rotavirus and enteric adenovirus infections were found among children below two years old (17)(18)(19)(20)(21).…”

Detection and molecular characterisation of adenovirus in children under 5 years old with diarrhoea

“…In different settings, the proportion of adenoviruspositive samples determined by EIA varied from 2.9%-16.7% (31)(32)(33)(34). The proportion of adenovirus positivity that we have identified in Turkey by EIA is concordant with that found in Europe.…”

Etiological Agents of Pediatric Diarrhea in Ardebil, Northwestern Iran

“…Rotavirus spread mainly occurs through fecal-oral route and contaminated hands (35); therefore, personal hygiene has a great impact on virus transmission. In the current study, similar to previous reports from Iran as well as other countries, the adenovirus had a lower rate compared with rotavirus (33). Also, there was no seasonal pattern for the adenovirus infection.…”

“…A study in Tehran revealed a prevalence of 19% for rotavirus infections, while another study from Ahvaz showed the prevalence of 35% for rotavirus infection (31,32). In another study, the rate of rotavirus positivity (42%) in Shiraz was higher than that of the current study results and the ones reported from other cities (33). It is considered that variety in the incidence of infection is associated with geographical conditions.…”