Frequency-Distribution Curve of Uric Acid in the General Population

Serum uric acid in England and Scotland.

“…Our findings cannot be taken to support this concept as far as the UK as a whole is concerned since, although the prevalence of hyperuricaemia in the men (Table 6) was higher than in one previous survey (Popert and Hewitt, 1962), it was very close to that in the other English group (Finn et al, 1966). Selection factors may explain, at least in part, national and international differences, though much higher prevalence rates for hyperuricaemia were found in the French and one Australian study (Zalokar et al, 1972;Jeremy and Towson, 1971).…”

“…They are also higher in men than those in a Finnish survey (Isomaki and Takkunen, 1969). They are similar to those of two surveys in the USA (Mikkel- Hall et al, 1967), a large French survey (Zalokar et al, 1972), and a smaller British study (Finn et al, 1966). They are considerably lower in both men and women than one other American survey (Acheson and O'Brien, 1966) and three Australasian surveys (Evans et al, 1969;Jeremy and Towson, 1971;Garrick et al, 1972).…”

“…Storage should only improve the reliability of the method as it allows nonspecific chromogens to decay (Buchanan et al, 1965). Comparison of our findings with those of earlier surveys is difficult because of the above provisos and also because earlier nonautomated colorimetric procedures tend to give lower readings, of the order of 0 4 mg/100 ml, than the automated method (Finn et al, 1966). Nevertheless, it is interesting to compare the present survey with the findings of other surveys in Caucasian adults of a similar age range to our subjects.…”

Relationship of Serum Uric Acid to Achievement Motivation

“…It has become apparent through clinical observation that hyperuricemia is considerably more widespread than gout, and that both are much more common in males than in females (5). Both conditions are, however, physiologically characterized by an excess of uric acid in the human organism (6). Hyperuricemia results from increased absorption of precursor purines, increased de novo purine production, diminished excretion or diminished breakdown of uric acid or some combination of these mechanisms (7).…”

Serum uric acid concentrations in a rural Tswana community in Southern Africa.

“…Indeed, in the 15th century, Galen ascribed gout to 'debauchery, intemperance, and a hereditary trait' (Finn, Jones, Tweedie, Hall, Dinsdale, and Bourdillon, 1966).…”