Frequency and predisposing factors of pharyngocutaneous fistula after total laryngectomy

The Novel Use of Flexible Endoscopic Techniques in the Management of Pharyngocutaneous Fistulas

“…1,2 PCFs contribute to prolonged hospital stays, increased hospital morbidity, delayed initiation of postoperative radiation therapy, delayed oral feeding, increased risk of carotid artery rupture, and recurrent hospitalizations. 3,4 Reported risk factors for the development of PCFs postlaryngectomy from a meta-analysis of 26 studies included postoperative hemoglobin level less than 12.5 g/dL, prior tracheotomy, preoperative radiotherapy, and preoperative radiotherapy with concurrent neck dissections. 1 Another study demonstrated that preoperative radiotherapy was the most significant risk factor for PCF formation, followed by diabetes, hepatic disease, preoperative chemotherapy, preoperative tracheostomy, and concurrent neck dissection.…”

“…1 Another study demonstrated that preoperative radiotherapy was the most significant risk factor for PCF formation, followed by diabetes, hepatic disease, preoperative chemotherapy, preoperative tracheostomy, and concurrent neck dissection. 4 Numerous approaches exist for the management of PCFs. Many small PCFs may be managed conservatively with local wound care and compression and drainage, which allow the fistula to heal by secondary intention.…”