Frequency and Determinants of Erectile Dysfunction in Italy

Parazzini, Fabio; Fabris, Fabrizio; Bortolotti, Angela; Calabrò, Antonino; Chatenoud, Liliane; Colli, Enrico; Landoni, M; Lavezzari, M; Turchi, P; Sessa, Aurelio; Mirone, Vincenzo

doi:10.1159/000020098

Cited by 200 publications

(144 citation statements)

References 17 publications

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“…Our initial search identified 221 articles, but only 11 cross-sectional studies [13][14][15][16][17][18][19][20][21][22] documented the adjusted OR for alcohol, another cross-sectional study 23 and a prospective cohort 24 from the same study population provided adjusted relative risks (RR), one cohort study 25 provided adjusted OR. Only the 11 cross-sectional studies that provided adjusted ORs will be included in the meta-analysis, since the other two cohort studies were of different study design, and the RR reported by the cross-sectional and cohort studies were derived with a different statistical method (Mantel-Haenszel rather than logistic regression).…”

Section: Resultsmentioning

confidence: 99%

“…However, caution has to be exercised in the extrapolation, as our results did not show a statistically significant OR for consuming 1-7 drinks/week, and did not demonstrate any harmful effects of alcohol on sexual function. In fact, three large studies 9,16,18 have demonstrated progressively smaller ORs of ED for increasing levels of alcohol consumption.…”

Section: Discussionmentioning

confidence: 99%

“…Alcohol consumption and erectile dysfunction JYW Cheng et al (95% CI, 12-22), 16% (11-23) and 15% (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24) in those with o1 drink/day, 1-3 drinks/day and X4 drinks/day of alcohol consumption respectively. This incidence figure was adjusted for age, active and passive smoking, overweight, hypertension, physical activity, cholesterol, fat intake, testosterone, depression and antihypertensive medication intake.…”

Section: Cohort Study (Mmas)mentioning

confidence: 99%

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Alcohol consumption and erectile dysfunction: meta-analysis of population-based studies

et al. 2007

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Alcohol is long regarded as a risk factor for erectile dysfunction (ED), but epidemiological evidence has been equivocal. We aimed to investigate the ED risk associated with various levels of alcohol consumption by meta-analysis. We searched for population-based studies on ED through Medline, PubMed, PsychInfo, and scanned through reference lists. Eleven cross-sectional studies were included and analyzed with random effects model. We reviewed the results from one crosssectional study and two cohort studies. Regular alcohol consumption was negatively associated with ED (odds ratio (OR) ¼ 0.79; 99% confidence interval (CI), 0.67-0.92; Po0.001). Consumption of 8 or more drinks/week significantly reduced the risk of ED (OR ¼ 0.85; 99% CI, 0.73-0.99; P ¼ 0.007), but consumption of less alcohol (1-7 drinks/week) was not significant (OR ¼ 0.73; 99% CI, 0.44, 1.20; P ¼ 0.101). Begg's test and Egger's test detected no significant publication bias. Our estimates (in sensitivity analyses) were rendered nonsignificant when International Index of Erectile Function definition was used and when statistical adjustment was made only for age. Meta-analysis of crosssectional studies yielded a protective association of alcohol on ED, but the two cohort studies did not demonstrate any significant findings for alcohol consumption. More research is needed to confirm whether alcohol is protective or is unrelated to ED development.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Cohort Study (Mmas)mentioning

confidence: 99%

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Alcohol consumption and erectile dysfunction: meta-analysis of population-based studies

et al. 2007

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“…ED has been shown to increase with increasing age with prevalence estimates in community-based populations ranging from less than 1 to 11% for men in their 40s to 15-79% for men 70 and over. [1][2][3][4][5][6][7][8][9][10][11][12][13] The wide variation in estimates may be partly because of the disparate definitions of ED between studies. Many of these studies focused largely on ED alone, and did not provide information on other important aspects of sexuality in men.…”

Section: Introductionmentioning

confidence: 99%

Distribution of the Brief Male Sexual Inventory in community men

et al. 2003

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The objectives of the study were to characterize male sexual functioning as related to age in community-dwelling older men. In 1989, a random sample of men aged 40-79 y (n ¼ 2115) without prior prostate surgery, prostate cancer, or other conditions known to affect voiding function (except benign prostatic hyperplasia) was invited (55% agreed) to participate in the Olmsted County Study of Urinary Symptoms and Health Status Among Men. In 1996, a previously validated male sexual function questionnaire was administered to the cohort. The questionnaire has 11 questions measuring sexual drive (two questions); erectile function (three) and ejaculatory function (two), as well as assessing problems with sex drive, erections, or ejaculation (three); and overall satisfaction with sex life (one). Each question is scored on a scale of 0-4, with higher scores indicating better functioning. Cross-sectional age-specific means ( 7 s.d.) for drive, erections, ejaculation, problems, and overall satisfaction declined from 5.2 ( 7 1.5), 9.8 ( 7 2.5), 7.4 ( 7 1.4), 10.7 ( 7 2.2), and 2.6 ( 7 1.0), respectively, for men in their 40s to 2.4 ( 7 1.6), 3.3 ( 7 3.4), 3.6 ( 7 3.2), 7.7 ( 7 3.8), and 2.1 ( 7 1.2) for men 70 y and older (all Po0.001). The cross-sectional decline in function with age was not constant, with age-related patterns differing by domain. The percentage of men reporting erections firm enough to have intercourse in the past 30 days declined from 97% (454/468) among those in their 40s to 51% (180/354) among those in their 80s (Po0.001). In age-adjusted analyses, men reporting regular sexual partners had statistically significantly higher levels of sex drive, erectile function, ejaculatory function, and overall satisfaction than those who did not report regular sexual partners. Sexual drive, erectile functioning, ejaculatory functioning, and overall sexual satisfaction in men show somewhat differing cross-sectional patterns of decline with advancing age. Active sexual functioning is maintained well into the 80s in a substantial minority of community-dwelling men.

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“…Erectile dysfunction (ED) is a common problem in men, 1 with relevant impact on quality of life. In consideration of the sensitive nature of the condition, it is often 'not recognized'.…”

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confidence: 99%

Did men with erectile dysfunction discuss their condition with partner and physicians? A survey of men attending a free call information service

et al. 2002

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We present data collected among men attending a free call service on information on erectile dysfunction (ED) activated in Italy during the period 1997 -1999. Their attitudes towards discussion with their partner and physician about the condition are considered. Each subject, was asked if he was affected by ED (defined as inability to achieve and maintain an erection sufficient for satisfactory sexual performance). In the case of a positive answer, the subject was asked if he had ever discussed his condition with partner or a physician. A total of 12 761 subjects with ED called the service: 7265 (56.9%) reported to have discussed their condition with their partner. The proportion tended to increase with duration of ED, being 47.9% in subjects reporting ED lasting < 6 months and 59.9% in those reporting ED lasting > 3 y (w 2 1 trend < 0.05). Likewise, the proportion of subjects reporting to have discussed ED with a physician was 50.3% (6416 subjects), being 33.6% in subjects with ED lasting < 6 months and 57.9% of those with ED lasting > 3 y (w 2 1 trend, P < 0.01). International Journal of Impotence Research (2002) 14, 256-258. doi:10.1038=sj.ijir.3900879Keywords: erectile dysfunction; psycosocial aspects; discussion Erectile dysfunction (ED) is a common problem in men, 1 with relevant impact on quality of life. In consideration of the sensitive nature of the condition, it is often 'not recognized'. This point is important, in consideration of the availability of effective drugs with a favourable safety profile. 2 It is generally thought that efforts should be made in order to increase discussion by men with ED with their partners and physicians about the condition. 3 The proportion of men with ED who have discussed their condition with their partner and physician is however unknown, and may be different in countries characterized by different cultural and social behaviours. Further, with the advent of Viagra, the problem of ED has been widely discussed for the first time, Viagra playing a key role in breaking down social barriers.In order to give some information on the attitudes of men with ED to discuss the condition, in this paper we present data collected from men attending a free call service focused on information on ED activated in Italy during the period 1998 -1999. This experience, although based on a selected population, may offer some information on the attitudes of subjects with ED to discuss their condition with their partner and physician in Italy. MethodsIn 1998 a free call information service on ED was started. The service was publicized in the lay press. Further, a mailing was made in order to inform urologists=andrologists and GPs about it.Each subject who called the service was asked if he was affected by ED (defined as inability to achieve and maintain an erection sufficient for satisfactory sexual performance). In the case of a positive answer, a brief questionnaire was filled including information on age, duration of the condition, area of residence, concomitant diseases related to ED, smo...

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Frequency and Determinants of Erectile Dysfunction in Italy

Cited by 200 publications

References 17 publications

Alcohol consumption and erectile dysfunction: meta-analysis of population-based studies

Alcohol consumption and erectile dysfunction: meta-analysis of population-based studies

Distribution of the Brief Male Sexual Inventory in community men

Did men with erectile dysfunction discuss their condition with partner and physicians? A survey of men attending a free call information service

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