Frequency and clinical correlates of bipolar features in acute coronary syndrome patients

Pini, Stefano; Abelli, Marianna; Gesi, Camilla; Lari, Lisa; Cardini, Alessandra; Paolo, Luca Di; Felice, Francesca; Stefano, Rossella Di; Mazzotta, Gianfranco; Oligeri, Claudia; Bovenzi, Francesco; Borelli, Lucia; Bertoli, Daniele; Michi, Paola; Muccignat, Alessandro; Micchi, J.; Balbarini, Alberto

doi:10.1016/j.eurpsy.2013.06.007

Cited by 7 publications

(2 citation statements)

References 43 publications

(56 reference statements)

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“…Data on patients’ demographics, medical history, clinical characteristics, electrocardiographic findings, ACS definition and treatment interventions, as well as in-hospital outcomes were reported in a detailed standardized case record form, adapted from the Blitz study, 20 by a trained cardiologist in each CICU. The details on symptoms onset, first medical help seeking, and arrival at hospital CICU were collected as soon as patients could be interviewed.…”

Section: Methodsmentioning

confidence: 99%

Clinical correlates of complicated grief among individuals with acute coronary syndromes

Pini¹,

Gesi²,

Abelli³

et al. 2015

NDT

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ObjectiveThe study aimed at exploring bereavement and complicated grief (CG) symptoms among subjects without a history of coronary heart disease (CHD) at the time of a first acute coronary syndrome (ACS) and to evaluate the relationship of CG symptoms and ACS.MethodOverall, 149 subjects with ACS (namely, acute myocardial infarct with or without ST-segment elevation or unstable angina), with no previous history of CHD, admitted to three cardiac intensive care units were included and evaluated by the Structured Clinical Interview for Complicated Grief (SCI-CG), Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, and the 36-item Short-Form Health Survey (MOS-SF-36).ResultsOf the total sample of 149 subjects with ACS, 118 (79.2%) met criteria for DSM-5 persistent complex bereavement disorder. Among these, subjects who lost a partner, child, or sibling were older (P=0.008), less likely to be working (P=0.032), and more likely to be suffering from hypertension (P=0.021), returned higher scores on the SCI-CG (P=0.001) and developed the index ACS more frequently between 12 and 48 months after the death than those who lost a parent or another relative (P≤0.0001). The occurrence of ACS 12–48 months (P=0.019) after the loss was positively correlated with SCI-CG scores. An inverse relationship with SCI-CG scores was observed for patients who experienced ACS more than 48 months after the loss (P=0.005). The SCI-CG scores significantly predicted lower scores on the “general health” domain of MOS-SF-36 (P=0.030), as well as lower scores on “emotional well-being” domain (P=0.010).ConclusionA great proportion of subjects with ACS report the loss of a loved one. Among these, the loss of a close relative and the severity of CG symptoms are associated with poorer health status. Our data corroborate previous data indicating a strong relationship between CG symptoms and severe cardiac problems.

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Section: Methodsmentioning

confidence: 99%

Clinical correlates of complicated grief among individuals with acute coronary syndromes

Pini¹,

Gesi²,

Abelli³

et al. 2015

NDT

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“…The presence of affective disorders (which, by definition, are persisting or recurrent conditions in the majority of cases) may have a pathoplastic effect on the bone marrow response to acute cardiac ischemic events. This issue has been crucially investigated by the Pisa group within the framework of the collaborative study on EPCs, depressive disorders and ischemic heart disease [ 91 , 92 , 95 ]. Further research is strongly warranted in this area.…”

Section: Epc From Bench To Bedside Literature Reviewmentioning

confidence: 99%

Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside

Morrone

Picoi

Felice

et al. 2021

IJMS

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Increased morbidity, mortality and length of in-hospital stay for patients with acute coronary syndrome with pre-morbid psychiatric diagnoses

Protty

Lacey

Smith

et al. 2017

International Journal of Cardiology

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Frequency and clinical correlates of bipolar features in acute coronary syndrome patients

Abstract: Our data indicate that bipolar features and diagnosis are frequent in ACS patients. Bipolar disorder has a negative impact on cardiac symptomatology. Further research in this area is warranted.

Cited by 7 publications

References 43 publications

Clinical correlates of complicated grief among individuals with acute coronary syndromes

Clinical correlates of complicated grief among individuals with acute coronary syndromes

Endothelial Progenitor Cells: An Appraisal of Relevant Data from Bench to Bedside

Increased morbidity, mortality and length of in-hospital stay for patients with acute coronary syndrome with pre-morbid psychiatric diagnoses

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