“…In the past, surgical solutions yielded negative results, and sometimes even culminated in amputation. Even with the evolution of treatment, many techniques are described, the most common being the Ilizarov external fixator through the distraction osteogenesis method with increased angiogenesis [2,3,10], intramedullary nailing with or without bone graft [4], and vascularised fibula graft have all been advocated for primary, or secondary surgery [3,7,17,19,21]. Advances in molecular biology have resulted in some recent studies that use recombinant human bone morphogenetic proteins for the treatment of CPT [12,16].…”