Free radical scavenging activity, flavonoid and phenolic contents of selected Ivorian plants

N'guessan, J. D.; Zirihi, Guédé Noël; Kra, Akm; Kouakou, K; Djaman, AJ; Guédé-Guina, F.

doi:10.4314/ijonas.v3i4.36155

Cited by 12 publications

(12 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, by the method of FRAP, the best antioxidant power has been recorded with the ethanol extract followed by the methanol extract. By this method, the EC 50 value of the aqueous extract is three (3) times greater than that of vitamin C. This difference may be due to the sensitivity to the reagents used in each of the methods [23]. In view of all the results, butanol extract recorded the highest levels of polyphenols as well as the best antioxidant activities.…”

Section: Discussionmentioning

confidence: 88%

Phytochimic Study, Antioxidant Activity and Nutritional Interest of Extracts from Leaves of Khaya senegalensis (Desr) A. Juss (Meliaceae) Collected in the Northern Cote d'ivoire

Monon

Zanga

Fernique

et al. 2019

JPRI

View full text Add to dashboard Cite

Medicinal and food plants contain a large number of metabolites that have multiple interests in pharmacology, cosmetology and the food industry. The aim of this study was to determine the content of phenolic and flavonoid compounds, to evaluate the antioxidant activity and to raise the Monon et al.; JPRI, 31(6): 1-10, 2019; Article no.JPRI.52509 2 nutritional interest of extracts from leaves of Khaya senegalensis. The methodological approach consisted of carrying out extractions with distilled water, ethanol, methanol and butanol. The extracts thus obtained were subjected to phytochemical analysis by spectrophotometric assay to determine the content of minerals, total phenols and flavonoids and to evaluate the antioxidant activity. The investigations revealed that K. senegalensis leaves extract have a high calcium content (948.38 ± 11.57 mg / 100 g), magnesium (188.24 ± 0.97 mg / 100 g), phosphorus (304.98 ± 2.6 mg / 100 g) and iron (41.50 ± 1.57 mg / 100 g). A high content of total phenols and flavonoids was observed with butanol extract (91.53 ± 0.04 mg EAG / g extract) and (75.58 ± 0.05 mg EQ / g extract) respectively. The ethanol and methanol extracts recorded the best performances by reducing the residual iron while the aqueous and butanol extracts obtained the IC 50 values closest to those of the reference viz vitamin C and BHT. This studyshowed that K. senegalensis leaves are a source of active substances known for their therapeutic and nutritional properties. The leaves of K. senegalensis could be used to treat various pathologies and also as an alternative in cattle feeding. Original Research Article

show abstract

Section: Discussionmentioning

confidence: 88%

Phytochimic Study, Antioxidant Activity and Nutritional Interest of Extracts from Leaves of Khaya senegalensis (Desr) A. Juss (Meliaceae) Collected in the Northern Cote d'ivoire

Monon

Zanga

Fernique

et al. 2019

JPRI

View full text Add to dashboard Cite

show abstract

“…The higher polyphenols concentration observed in laper and placo could be very interesting because the polyphenolic compounds are used more and more in therapeutic [37]. In addition, N'guessan et al (2007) [38] showed the existence of a correlation between the total phenols content and the free radical scavenging activity. Zinc is essential for human development and function.…”

Section: Discussionmentioning

confidence: 94%

Evaluation of Antioxidant Activities and Estimation of Zinc Content of Aqueous and Methanolic Extracts of Three Medicinal Plants: Cochlospermum Planchonii, Pericopsis Laxiflora and Harungana Madagascariensis

Jeanne¹,

Brice²,

Dieudonné³

et al. 2016

ijbb

View full text Add to dashboard Cite

Malaria disease is a pathology which occurs as a result of the oxidative stress. Three plants of the Ivorian pharmacopoeia are particularly used in the traditional medicine for the treatment of malaria in Côte d'Ivoire. They are Cochlospermum planchonii (Placo), Pericopsis laxiflora (Laper) and Harungana madagascariensis (Madhar).The objective of this study was to evaluate the in vitro antioxidant activity of the aqueous and methanolic extracts of three medicinal plants of Côte d'Ivoire. The quantitative measurement of total flavonoids gave the following results: Laper (560.80 mg QE/g ± 7.40), Madhar (352.50 mg QE/g ± 9.46) and Placo (314.20 mg QE/g ± 4.41). The total polyphenols were more concentrated in Laper (262.50 mg GAE/g ± 9.47) and Placo (203.20 mg GAE/g ± 2.21). Noticeable zinc content was found in Laper (13.56 ppm) and Placo (11.40 ppm) against 3.43 ppm in Madhar. The radical scavenging activity by 2,2-diphenyl-1-picryl hydrazyl (DPPH) and antiradical power measurement by ABTS (2,2' azino bis-3-ethylbenzothiazoline-6-sulphonic acid) assay have showed good activity for Laper (IC 50 = 7.50 µg/mL) and placo (IC 50 = 8.01 µg/mL). The standard antioxidant compound (quercetin) gave an IC 50 = 4.00 µg/mL. This study suggested that the high content of total flavonoids, total phenols and minerals in these plants could partly justify the therapeutic use of at least two of the three plants.

show abstract

“…Moreover, the fight against free radicals requires the intervention of radical scavengers. Some groups of plant secondary metabolites such as phenolic acids and flavonoids [ 19 , 20 , 21 ] have high antioxidant activities. Their mechanisms of action are trapping and chelating of free radicals [ 22 ] Indeed, these metabolites have the peculiarity to give up easily an electron or a proton in order to neutralize free radicals [ 15 ].…”

Section: Resultsmentioning

confidence: 99%

Bio-guided Isolation of Antioxidant Compounds from Chrysophyllum perpulchrum, a Plant Used in the Ivory Coast Pharmacopeia

et al. 2010

View full text Add to dashboard Cite

Chrysophyllum perpulchrum (Sapotaceae) is used in the traditional Ivory Coast pharmacopeia to cure fevers. The extract of C. perpulchrum used for this study was the powdered form obtained from the maceration of the dried plant bark in 96% methanol, followed by evaporation to dryness. In the present study, the antioxidative and radical-scavenging activities of the methanolic extract were studied with three standard biological tests: DPPH reduction, ferric thiocyanate (FTC) lipidic peroxidation inhibition and thiobarbituric acid reacting substances (TBARS). Gallic acid and quercetin were used as references. The total amount of phenolic compounds in the extract was determined by ultraviolet (UV) spectrometry and calculated as gallic acid equivalents. Catechin and two dimeric procyanidins were found to be the compounds responsible for the activities. They were chemically dereplicated in the extract by LC-MS. For quantitation purposes, they were isolated by successive chromatographic methods and characterized by mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectrometry. The quantities of these compounds in C. perpulchrum were 5.4% for catechin (P1), and 5.6 and 9.2% for dimers (compounds 2 (P2) and 3 (P3)), respectively. They displayed antioxidant activity with IC50 values of 2.50 ± 0.15 µg/mL (P1), 2.10 ± 0.2 µg/mL (P2) and 2.10 ± 0.1 µg/mL (P3). The total extract, the active fractions and the pure compounds inhibited the lipid peroxidation by the FTC method and the TBARS method in the range of 60%. These values were comparable to those seen for quercetin.

show abstract

Free radical scavenging activity, flavonoid and phenolic contents of selected Ivorian plants

Cited by 12 publications

References 0 publications

Phytochimic Study, Antioxidant Activity and Nutritional Interest of Extracts from Leaves of Khaya senegalensis (Desr) A. Juss (Meliaceae) Collected in the Northern Cote d'ivoire

Phytochimic Study, Antioxidant Activity and Nutritional Interest of Extracts from Leaves of Khaya senegalensis (Desr) A. Juss (Meliaceae) Collected in the Northern Cote d'ivoire

Evaluation of Antioxidant Activities and Estimation of Zinc Content of Aqueous and Methanolic Extracts of Three Medicinal Plants: Cochlospermum Planchonii, Pericopsis Laxiflora and Harungana Madagascariensis

Bio-guided Isolation of Antioxidant Compounds from Chrysophyllum perpulchrum, a Plant Used in the Ivory Coast Pharmacopeia

Contact Info

Product

Resources

About