Free-Floating Iris Cyst in a Patient with Recurrent Iritis

Teong, Joanne M.Y.; Adler, P; Fuzzard, Dujon

doi:10.1159/000432393

Cited by 5 publications

(5 citation statements)

References 9 publications

(13 reference statements)

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“…There have been at least 10 prior case reports describing free-floating cysts in the AC, the first published over 40 years ago [4,5,6,7,8,9,10,11,12,13]. Nearly all of these case reports describe 1 unilateral solitary free-floating cyst in a single patient.…”

Section: Discussionmentioning

confidence: 99%

Free-Floating, Pigmented Cysts in the Anterior Chamber Causing Ocular Hypertension

2016

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Purpose: The aim of this study was to describe the clinical and histopathological features of a 36-year-old male with hundreds of recurrent, unilateral, free-floating, pigmented cysts in the anterior chamber causing ocular hypertension. Procedures: The patient was referred to ocular oncology for blurry vision of the right eye and was found to have myriad pigmented, free-floating cysts in the anterior chamber and heavy pigmentation of the angle on gonioscopy. Anterior chamber washout was performed, and the fluid recovered was sent for pathological analysis. Results: The pathology report demonstrated rare nonpigmented epithelial cells, more consistent with iris stromal cysts or secondary implantation epithelial cysts. Conclusions: This paper highlights the first documented case of innumerable spontaneously occurring, unilateral, free-floating, pigmented cysts in the anterior chamber. While clinical diagnosis suggested iris pigment epithelial cysts, pathology suggested iris stromal cysts or secondary implantation epithelial cysts.

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Section: Discussionmentioning

confidence: 99%

Free-Floating, Pigmented Cysts in the Anterior Chamber Causing Ocular Hypertension

2016

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“…The recurrence time of iris cysts was reported to range from 6 weeks to 5 years depending on different surgical treatment methods 19 – 21 . To avoid recurrence, Shields et al 22 advised to perform an aspiration and light cryotherapy, and recommended a non-vitrectomy technique to prevent the inflammatory reaction and epithelial downgrowth.…”

Section: Discussionmentioning

confidence: 99%

Long-term outcomes of “open iridectomy” for secondary anterior chamber epithelial iris cysts

Lan

Liu

Huang

et al. 2021

Sci Rep

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Epithelial cysts run a high risk of recurrence and conversion to sheet-like ingrowth after surgical intervention. In this retrospective study, we introduced a modified iridectomy for treatment of secondary epithelial iris cysts (EICs) in the anterior chamber. Twenty-nine patients (29 eyes) aged 2–61 years received “open iridectomy” for EICs between April 1995 and July 2019. After viscodissection, most of the cyst wall was cut using a 20-gauge aspiration cutter via a 2.5-mm clear corneal incision. The residue closely adhering to the iris stroma was remained to avoid photophobia and diplopia. At 3 months, best corrected visual acuity was ≥ 20/100 in 55.5% (15/27, except two pediatric patients with poor cooperation) of patients. Among the eight patients suffering partial corneal edema preoperatively, six patients received surgery treatment at 3–6.5 months, and the cornea in the other two patients became transparent after medication. In a mean follow-up of 47.4 months, recurrence occurred in 3 patients at 7, 37, and 118 months, respectively. The percentage of treatment success was 96%, 87%, and 65% at 1, 5, and 10 years, respectively. “Open iridectomy” was effective for EICs, with a minimal invasion, less damage to the corneal endothelium, and a low recurrence rate.

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“…Zysten der Iris wurden bei Uveitiden wie der Heterochromiezyklitis, aber auch bei Herpes zoster beschrieben [3]. In einem gut dokumentierten Fall konnte die Entstehung einer FZV nach mehreren Rezidiven einer Iritis auf dem Boden einer HLA-B27-positiven rheumatoiden Arthritis nachgewiesen werden [8]. Parasitäre Infektionen können ebenfalls zur Bildung von FZV führen.…”

Section: Zysten Inflammatorischer Geneseunclassified

Frei fluktuierende intraokulare Zysten

Werner

Lang

Enders

2017

Klin Monatsbl Augenheilkd

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Patient 1 had a FZV as an incidental finding which had a smooth surface, a slight pigmentation and was translucent. The ultrasound biomicroscopy revealed an echo-free interior space. Without the patient's discomfort and missing treatment indication, a watch-and-wait strategy was chosen. Cysts of the iris can be classified as primary and secondary cysts. Primary cysts of the iris can arise from the stroma as the pigment epithelium wherein it is believed that FZV descend from the pigment epithelium. Secondary cysts and FZV can be generated by tumors, inflammation, epithelial ingrowth, the use of eye-drops or intraocular foreign bodies. Patient 2 showed marked myopic fundus changes and an FZG with a yellowish-greenish surface; the transparency was reduced and the surface was not pigmented. The ultrasound examination also revealed an echo-free interior space. Clinical controls were advised. Congenital and acquired causes are discussed for the formation of FZG. FZG could originate from the pigment epithelium of the iris, but there are conflicting study results. Trauma, inflammation and chorioretinal diseases are considered as a reason for acquired causes of FZG. The genesis, especially of FZG, is still unclear. For the treatment of patients with FZV and FZG, it is important to know the potential causes to be able to make a therapeutic decision. High quality photographic and sonographic documentation is needed in the watch-and-wait strategy.

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Free-Floating Iris Cyst in a Patient with Recurrent Iritis

Cited by 5 publications

References 9 publications

Free-Floating, Pigmented Cysts in the Anterior Chamber Causing Ocular Hypertension

Free-Floating, Pigmented Cysts in the Anterior Chamber Causing Ocular Hypertension

Long-term outcomes of “open iridectomy” for secondary anterior chamber epithelial iris cysts

Frei fluktuierende intraokulare Zysten

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