Fragrance material review on terpineol

Bhatia, S.P.; McGinty, D.; Foxenberg, R.J.; Letizia, C.S.; Api, A.M.

doi:10.1016/j.fct.2008.06.075

Cited by 10 publications

(5 citation statements)

References 9 publications

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“…3-Cyclohexene-1-methanol has been reported to have anticancer activity [38]. Because of its pleasant lilac-like odour, α-Terpineol is widely used in the manufacturing of cosmetics, soaps, perfumes, and antiseptic agents, and is considered one of the most frequently used fragrance compounds [39]. α-Terpineol demonstrated anti-proliferative (antioxidant) activity, which could be used in cancer prevention or treatment.…”

Section: Chemical Composition By Gc-ms Analysismentioning

confidence: 99%

GC-MS Analysis of Volatile Constituents, Antibacterial Activity, and Mechanism of Action of the Essential Oil from Cinnamomum Cassia Bark Against Vancomycin-Resistant Enterococci

Jha¹,

Gaikwad²

2022

J Biotechnol Bioinforma Res

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Background & Objectives: An alarming rise in multi-drug resistant bacterial pathogen like Vancomycin-resistant Enterococci (VRE) has culminated in a global health threat in today’s healthcare environment and has caused significant morbidity and mortality in patients. The field of medicinal herbs has developed at an exponential rate in subsequent decades. Acknowledging the antimicrobial mechanisms of essential oils and their components is vital for developing them as a potential new source of antibiotics that can work as an alternative treatment for multi-drug resistant bacterial infections. Methods: The current study investigates the physiochemical properties and a variety of analytical and biological activities to determine the activity of Cinnamomum cassia essential Oil against drug-resistant microorganisms by utilizing a Time kill curve and evaluating the Minimum Inhibitory Concentration (MIC) of oil. The antimicrobial properties were assessed using a growth curve and the cell membrane’s integrity. The essential oil was retrieved by hydro-distilling Cinnamon bark, and the volatile components of the essential oil were determined by Gas Chromatography-Mass Spectrometry (GC-MS). Result: GC-MS analysis detected major components such as Cinnamaldehyde-(E) (37.40%); 2-Propenal, 3-phenyl (11.70%) and 1,6-Octadien-3-ol,3,7- dimethyl- (5.97%). The minimum inhibitory concentration (MIC) and growth curves against VRE were also evaluated. The liberation of cellular contents, as well as changes in cell membrane permeability, have been studied. The MIC value of the essential oil against Vancomycin-resistant Enterococci was 15.625 μg/mL speculating that the essential oil seemed to be effective against the drug-resistant culture. When the essential oil of Cinnamomum cassia was administered to the bacterial culture, the constituents of the bacterial cell were expelled into the medium.

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Section: Chemical Composition By Gc-ms Analysismentioning

confidence: 99%

GC-MS Analysis of Volatile Constituents, Antibacterial Activity, and Mechanism of Action of the Essential Oil from Cinnamomum Cassia Bark Against Vancomycin-Resistant Enterococci

Jha¹,

Gaikwad²

2022

J Biotechnol Bioinforma Res

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“…The worldwide demand for pine derived chemicals including turpentine and its derivatives are projected to reach 5.27 billion USD by 2021 [ 4 ] with Indonesia as the third largest producer after China and Brazil. One important derivative of turpentine is terpineol that mainly used as disinfectant for soap, flavouring agent, and pharmaceutical substances [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

A method to control terpineol production from turpentine by acid catalysts mixing

Prakoso

Putra

Handojo

et al. 2020

Heliyon

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Terpineol, a promising valorisation product of pine industry, is widely used as an active ingredient for disinfectant soap, cleansers, perfumes, and pharmaceutical purposes. Synthesis of terpineol is generally carried out by separation of α-pinene compounds from crude turpentine through fractionation and then hydrated (addition of water) with the help of acid catalysts. However, direct turpentine hydration without pre-fractionation process can be more beneficial from economic and process point of views. This study aims to investigate the effect of both single and mixed/combined catalysts towards terpineol yield. Combined strong and weak acid catalysts were required to obtain high feed conversion and terpineol yield. The selectivity of terpineol is then correlated to the solubility of a weak/organic acid. In this study, the highest yield of terpineol was 54.0 ± 8.2%-w/w using combination of formic acid and sulphuric acid.

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“…The toxicity of α‐terpineol in animals has been extensively studied in skin and mucosa, and no toxic effects have been observed after short‐ or long‐term exposure . Moreover, α‐terpineol has traditionally been used in shampoos, toilet soaps, and decorative fine fragances …”

mentioning

confidence: 99%

“…The toxicity of α-terpineol in animals has been extensively studied in skin and mucosa, and no toxic effects have been observed after short-or long-term exposure. [24][25][26] Moreover, αterpineol has traditionally been used in shampoos, toilet soaps, and decorative fine fragances. 23 Thus, the purpose of this in vitro study was to assess the efficacy of a terpenic denture cleanser in denture biofilm removal, using scanning electron microscopy (SEM), and to compare the activity with two commercially available cleaning solutions.…”

mentioning

confidence: 99%