Abstract:The present paper deals with the influence of material variability on the seismic vulnerability assessment of reinforced concrete buildings. Existing r.c. buildings are affected by a strong dispersion of material strengths of both the base materials. This influences the seismic response in linear and nonlinear static analysis. For this reason, it is useful to define a geometrical parameter called "material eccentricity". As a reference model, an analysis of a two storey building is presented with a symmetrical plan but asymmetrical material distribution. Furthermore, an analysis of two real buildings with a similar issue is performed. Experimental data generate random material distributions to carry out a probabilistic analysis. By rotating the vector that defines the position of the center of strength it is possible to describe a strength domain that is characterized by equipotential lines in terms of the Risk Index. Material eccentricity is related to the Ultimate Shear of non-linear static analyses. This relevant uncertainty, referred to as the variation of the center of strength, is not considered in the current European and Italian Standards. The "material eccentricity" therefore reveals itself to be a relevant parameter to considering how material variability affects such a variation.