Fragilidade física e desempenho cognitivo em populações idosas, parte I: revisão sistemática com metanálise

Furtado, Guilherme Eustáquio; Letieri, Rubens Vinícius; Hogervorst, Eef; Teixeira, Ana Maria; Ferreira, José Pedro

doi:10.1590/1413-81232018241.03692017

Cited by 17 publications

(9 citation statements)

References 63 publications

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“…As a heterogeneous geriatric syndrome, the pathogenesis of cognitive frailty has not been clarified, which may be related to hormones, inflammatory responses, cardiovascular risk factors, and so on (Panza et al, 2018). Cognitive impairment and physical frailty have similar time trajectories and pathological mechanisms (Furtado et al, 2019), and they interact with each other.…”

Section: Discussionmentioning

confidence: 99%

Cognitive frailty as a predictor of adverse outcomes among older adults: A systematic review and meta‐analysis

Huang

Xue

et al. 2020

Brain and Behavior

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Objective A systematic review and meta‐analysis basing on the prospective cohort studies were conducted to explore the risk of all‐cause mortality and dementia in cognitively frail older adults compared to robust older adults and to determine whether it was a predictor of adverse outcomes. Methods Pubmed, Web of Science, The Cochrane Library, EMBASE, and CINAHL databases were searched to retrieve studies on adverse outcomes of cognitive frailty. Two reviewers independently screened the literature, extracted data, and assessed the risk of bias of the included studies. Stata 15.0 Software was used to perform the meta‐analysis. The all‐cause mortality and dementia were observed to be the primary outcomes, while the other data were considered as the secondary outcome. Results A total of 14 studies were included in qualitative analysis and 12 studies were included in the meta‐analysis, with low risk of bias and moderate to good methodological quality. The results showed that cognitive frailty in older people had a higher risk of all‐cause mortality [HR = 1.93, 95%CI (1.67, 2.23), p < .001] and dementia [HR = 3.66, 95%CI (2.86, 4.70) as compared with robust. The subgroup analysis showed that the assessment tools were the main source of heterogeneity. Conclusion In older adults living in communities, the cognitive frailty was found to be a significant predictor of all‐cause mortality and dementia. Nonetheless, cognitive frailty was found to be a better predictor of all‐cause mortality and dementia than just frailty.

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Section: Discussionmentioning

confidence: 99%

Cognitive frailty as a predictor of adverse outcomes among older adults: A systematic review and meta‐analysis

Huang

Xue

et al. 2020

Brain and Behavior

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“…Of the pooled sample (n=26,935), 11,265 older adults (41.82%) were classified as pre-frail and 2,460 (9.13%) as frail. 22 Thus, when comparing these results to the findings of this study, one must consider the socioeconomic differences between the contexts and countries where the research was conducted. Studies conducted in developed countries, which have a high Human Development Index, showed lower rates of frail elderly when compared to developing countries, such as Brazil.…”

Section: Discussionmentioning

confidence: 89%

Family insuficiency and the condition and the physical frailty’s components of elderly in ambulatorial care

et al. 2022

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Objective to analyze the relationship between family insufficiency and the condition and the markers of physical frailty of elderly people followed up in a Geriatrics and Gerontology outpatient clinic. Method a quantitative and cross-sectional study conducted with 384 elderly (≥ 60 years) selected by pre-established inclusion and exclusion criteria. Physical frailty was assessed according to the frailty phenotype and family insufficiency by the Family APGAR. Data was analyzed using descriptive statistics and univariate analysis using the chi-square test with a statistical significance level of p≤0.05. Results there was no association between family insufficiency and physical frailty (p=0.344), however, it was observed a percentage of frail elderlies with high Family Dysfunction (22.2%) and moderate Family Dysfunction (19.4%), higher than that observed among the elderly with good family functioning (12.2%). Among the frail elderly for the marker “fatigue/exhaustion”, there was a direct proportionality to the degree of Family Dysfunction and a statistically significant relation to the total score of the Family APGAR (p=0.001). Conclusion and implications for the practice family frailty in the elderly is related to other intra-family factors and not exclusively to physical frailty, however, it can be stated that the degree of physical frailty among the elderly is directly proportional to the level of Family Dysfunction.

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“…Da amostra agrupada (n=26.935), 11.265 idosos (41,82%) foram classificados como pré-frágeis e 2.460 (9,13%) como frágeis. 22 Dessa forma, ao comparar esses resultados aos achados deste estudo, é preciso considerar as diferenças socioeconômicas entre os contextos e os países onde as pesquisas foram realizadas. Os estudos realizados em países desenvolvidos, que possuem um Índice de Desenvolvimento Humano elevado, mostraram taxas menores de idosos frágeis quando comparados aos países em desenvolvimento, como é o caso do Brasil.…”

Section: Discussionunclassified

Insuficiência familiar e a condição e os marcadores de fragilidade física de idosos em assistência ambulatorial

et al. 2022

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RESUMO Objetivo analisar a relação entre insuficiência familiar e a condição e os marcadores de fragilidade física de idosos acompanhados em ambulatório de Geriatria e Gerontologia. Método estudo quantitativo e transversal realizado com 384 idosos (≥ 60 anos) selecionados por critérios pré-estabelecidos de inclusão e exclusão. Avaliaram-se a fragilidade física segundo o fenótipo da fragilidade e a insuficiência familiar pelo APGAR de Família. Analisaram-se os dados mediante a estatística descritiva e a análise univariada mediante o teste de qui-quadrado com nível de significância estatístico de p≤0,05. Resultados não houve associação entre insuficiência familiar e fragilidade física (p=0,344), entretanto, observou-se percentual de idosos frágeis com elevada Disfunção Familiar (22,2%) e moderada Disfunção Familiar (19,4%), maior que o observado entre os idosos com boa funcionalidade familiar (12,2%). Entre os idosos frágeis para o marcador “fadiga/exaustão”, houve proporcionalidade direta ao grau de Disfunção Familiar e relação estatisticamente significativa ao escore total do APGAR de Família (p=0,001). Conclusão e implicações para a prática a insuficiência familiar no idoso está relacionada a outros fatores intrafamiliares e não exclusivamente à fragilidade física, no entanto, pode-se afirmar que o grau de fragilidade física entre os idosos é diretamente proporcional ao nível de Disfunção Familiar.

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Fragilidade física e desempenho cognitivo em populações idosas, parte I: revisão sistemática com metanálise

Cited by 17 publications

References 63 publications

Cognitive frailty as a predictor of adverse outcomes among older adults: A systematic review and meta‐analysis

Cognitive frailty as a predictor of adverse outcomes among older adults: A systematic review and meta‐analysis

Family insuficiency and the condition and the physical frailty’s components of elderly in ambulatorial care

Insuficiência familiar e a condição e os marcadores de fragilidade física de idosos em assistência ambulatorial

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