Fracture resistance of weakened bovine teeth after long‐term use of calcium hydroxide

Valera, Márcia Carneiro; Albuquerque, Maria Tereza Pedrosa de; Yamasaki, Mayra Cristina; Vassallo, Flávia Nicolle Stefani; Silva, Denise Almeida e Silva Alves da; Nagata, Juliana Yuri

doi:10.1111/edt.12185

Cited by 25 publications

(27 citation statements)

References 35 publications

(42 reference statements)

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“…Calcium hydroxide is the most commonly used root canal dressing for late replantation, and it is considered to be the medication of choice due to its alkaline pH and bactericidal effects, which may slow or limit inflammatory and replacement resorption . To observe these effects, a long application time with successive changes is required, which has been associated with a detrimental effect on the fracture resistance of root dentin . Additionally, as observed in this research, studies in animal models have demonstrated that calcium hydroxide is ineffective in preventing inflammatory and replacement resorption following tooth replantation .…”

Section: Discussionmentioning

confidence: 79%

Anti‐inflammatory and anti‐resorptive efficacy of adrenergic blockers on late replanted rat incisors

Matos

Prado

Khoury

et al. 2019

Dental Traumatology

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Background/Aim: In addition to their anti-inflammatory and anti-osteoclastogenesis properties, adrenergic blockers may also have promising anti-resorptive effects that can prevent root resorption when teeth are replanted because of avulsion. The aim of this study was to investigate the effects of phentolamine (Ph) and propranolol (Pr) in gels on the repair process of late replanted rat incisors. A further aim was to evaluate the biocompatibility of both drugs to human periodontal ligament fibroblasts (HPDLFs). Materials and methods:Forty-eight maxillary right incisors were extracted from male Wistar rats, stored in paper napkins for 60 minutes, and randomly allocated to one of eight groups (n = 6). The root canal, root surface, and alveolus were treated with 0.75 µg/mL Ph gel (Ph0.75), 10 µg/mL Ph gel (Ph10), 100 µg/mL Ph gel (Ph100), 2.5 µg/mL Pr gel (Pr2.5), 10 µg/mL Pr gel (Pr10), 100 µg/mL Pr gel (Pr100), or sodium carboxymethylcellulose gel (CMC) before replantation. In the control group (CH), only the root canal was treated with calcium hydroxide paste. Thirty days following surgery, the animals were euthanized, and the right hemimaxilla was removed to perform micro-CT and histomorphometric analysis to determine osteoclastic activity.Ethanolic solutions of Ph10 and Pr10 were selected based on the in vivo study, and the viability of HPDLFs stimulated with lipopolysaccharide was determined by MTT assays. Results:The micro-CT and histomorphometric analysis revealed no significant differences among the treatments (P > .05). The presence of active osteoclasts was significantly decreased in the Ph10 and Pr10 groups (P < .05). Ph10 and Pr10 produced statistically similar cell survival rates compared to the control group (P > .05). Conclusions: Ph10 and Pr10 significantly decreased osteoclastogenesis in delayedreplanted rat teeth and were not cytotoxic toward HPDLFs. K E Y W O R D Sadrenergic blockers, phentolamine, propranolol, root resorption, tooth avulsion, tooth replantation

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Section: Discussionmentioning

confidence: 79%

Anti‐inflammatory and anti‐resorptive efficacy of adrenergic blockers on late replanted rat incisors

Matos

Prado

Khoury

et al. 2019

Dental Traumatology

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“…There is limited number of studies in the literature about the effects of CHX on the fracture strength of teeth. In the Valera et al study [28], irrigation with 2% CHX showed a significantly lower fracture resistance than that of the control group. As an intracanal medicament, 0.5% CHX was added to CH in Prabhakar et al's study [29], and the mixture was applied to the root canal for 30 days.…”

Section: Discussionmentioning

confidence: 82%

Effects of intracanal medicaments and the remaining cavity wall on fracture strength of endodontically treated molars

Olcay

Coban²,

Bellí

2018

BDS

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Objective: The aim of this study was to investigate the effects of the short-term intracanal application of two medicaments on the fracture strength of root-filled molar teeth with different levels of tooth structure loss. Material and Methods: Standard access cavities of totally 84 intact maxillary molar teeth were prepared in 72 teeth and were divided into 3 main groups. Standard access cavities were kept in the first group, while mesio-occlusal-distal cavities (MOD) were prepared in the second and third groups. One-half of the palatinal walls were removed in the third group. Twelve sound teeth were used in the fourth group as control. Each group was then assigned into two subgroups according to the medicament used (n=12): 2% chlorhexidine gel and calcium hydroxide. Samples were stored at 37°C and 100% humidity for 1 week. Then the teeth were inserted into a universal testing machine and vertically loaded (5 mm/min) from the occlusal surface. The data was recorded in Newtons and statistically evaluated using a Univariate ANOVA and a Tukey as post hoc test. Results: A significant difference was found among the test groups (p<0.01). No significant difference was found according to the medicament used (p>0.05), however the number of remaining walls significantly affected the fracture strength (p<0.01). The first group with access cavity showed mostly repairable fractures (60%–80%) whereas the others showed mostly non-repairable fracture patterns (60%–90%). Conclusion: In conclusion, the fracture strength of endodontically treated teeth is related to the structure loss rather than the intracanal medicament used. KeywordsEndodontically treated teeth; Fracture strength; Intracanal medicament; Remaining cavity wall; Root facture.

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“…In addition, many studies have used them for laboratory investigations, including studies on root and crown fractures. [17][18][19] To reduce variations, factors, such as root length and root dentin thickness were standardized to 20 and 2.5 mm respectively, similar to the 2012 study by Alsamadani et al 20 Some authors have employed impression materials to simulate the periodontal ligament. 18,21 The periodontium effect was not reproduced in this study, and all roots were embedded directly in PVC cylinders with acrylic resin, 2 mm below the cementoenamel junction.…”

Section: Discussionmentioning

confidence: 99%

Effect of Endodontic Irrigation Protocols on Crown Fracture Resistance

Baechtold

Cunha

Souza

et al. 2018

The Journal of Contemporary Dental Practice

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Fracture resistance of weakened bovine teeth after long‐term use of calcium hydroxide

Abstract: Apexification with periodic changes of calcium hydroxide medicament leads to weakness of the teeth independent of the irrigation solution used.

Cited by 25 publications

References 35 publications

Anti‐inflammatory and anti‐resorptive efficacy of adrenergic blockers on late replanted rat incisors

Anti‐inflammatory and anti‐resorptive efficacy of adrenergic blockers on late replanted rat incisors

Effects of intracanal medicaments and the remaining cavity wall on fracture strength of endodontically treated molars

Effect of Endodontic Irrigation Protocols on Crown Fracture Resistance

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