Fractional exhaled nitric oxide change in pediatric patients after emergency department care of asthma exacerbations

Karlin, Eric; Gebretsadik, Tebeb; Peebles, R. Stokes; Hartert, Tina V.; Langley, Emily W.; Arnold, Donald H.

doi:10.1016/j.anai.2014.11.002

Cited by 3 publications

(2 citation statements)

References 6 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further evidence that FeNO levels increase with asthma exacerbations is shown by Karlin et al, who have shown FeNO levels decreased by 23.8% after resolution of an asthma exacerbation [67]. This study also showed that African-American children with asthma exacerbations had higher FeNO levels than compared with Caucasian children (median FeNO of 45 vs. 32 ppb).…”

Section: Feno and Asthma Exacerbationssupporting

confidence: 68%

An Overview of Fractional Exhaled Nitric Oxide and Children with Asthma

Rao

Phipatanakul

2016

Expert Review of Clinical Immunology

View full text Add to dashboard Cite

SUMMARY Asthma is the most common pediatric chronic disease and is characterized by lung inflammation. Fractional exhaled nitric oxide (FeNO) is thought to reflect the presence of eosinophilic airway inflammation, and is an easy, non-invasive test that has held promise in providing additional objective data. However, not all studies have shown a clinical benefit in the use of FeNO to guide management of asthma in children. This review will describe the results of the most recent studies examining the use of FeNO in the diagnosis and treatment of asthma in infants, pre-school-aged children and in school-aged children. It will aid the clinician in providing a clinical context in which FeNO may be most useful in treating pediatric asthma.

show abstract

Section: Feno and Asthma Exacerbationssupporting

confidence: 68%

An Overview of Fractional Exhaled Nitric Oxide and Children with Asthma

Rao

Phipatanakul

2016

Expert Review of Clinical Immunology

View full text Add to dashboard Cite

show abstract

“…As observed in younger children, higher FeNO indicates worse asthma severity in a population of inner-city adolescents. [ 67 ] Karlin et al [ 68 ] found elevated FeNO during asthma exacerbations, which decreased when asthma control improved.…”

Section: Fractional Exhaled Nitric Oxide (Feno)mentioning

confidence: 99%

Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice

Sánchez‐García

Mena

Quirce

2017

European Clinical Respiratory Journal

View full text Add to dashboard Cite

Asthma is a common disease in both high and lower income countries that starts early and persists often for life. A correct and accurate diagnosis, treatment and follow-up during childhood are essential for a better understanding of adult asthma and avoiding over- or under-treatment.Th2 inflammation in children with asthma symptoms is usually assessed by measuring with serum total IgE, blood eosinophilia and FeNO levels that may help to predict asthma, particularly in those infants and young children in whom lung function tests are difficult to perform. FeNO measurement, compared to intra-individual levels, may be useful also for ascertaining treatment adherence. Nevertheless, an isolated measurement may be insufficient and only the combination of these markers improves the diagnosis, phenotyping and follow-up of an asthmatic child.

show abstract