Fournier's gangrene: not as lethal as previously thought? A case series

Heijkoop, Bridget; Parker, Natalie; Spernat, Daniel

doi:10.1111/ans.14760

Cited by 12 publications

(19 citation statements)

References 7 publications

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“…Fournier's gangrene is known to be a rapid onset disease, but studies have shown that application to the hospital is delayed by an average of one week after initial symptoms have presented. [13] In our study, the median time from symptom onset to hospital application was four (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) days. Immediate diagnosis and treatment of FG are known to affect prognosis.…”

Section: Discussionmentioning

confidence: 64%

“…The age of the patients hospitalized in the intensive care unit (ICU) was found to be higher than the patients who did not require ICU admittance (65.33±11.63 years vs. 54.39±11.79 years, respectively; p=0.013). Median FGSI score was 2 (0-14), while the median UFGSI score was 4 (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). Median FGSI and UFGSI scores were found to be higher in patients accepted to the ICU compared to those who were not (4 vs. 2, p=0.025; and 6 vs. 3, p=0.002, respectively).…”

Section: Resultsmentioning

confidence: 99%

“…Immediate diagnosis and treatment of FG are known to affect prognosis. [4] Thus, these intervals have a significant impact on diagnosis and the success of treatment.…”

Section: Discussionmentioning

confidence: 99%

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Fournier’s Gangrene: Five Years’ Experience from a Single Center in Turkey

Hatipoğlu¹

2020

Ulus Travma Acil Cerrahi Derg

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BACKGROUND: Is the present study aims to analyze demographic, clinical and surgical data of all patients with FG (Fournier's gangrene) admitted to a tertiary healthcare hospital in the largest city of Turkey. METHODS:This study included 35 patients with Fournier's gangrene, who were followed by the General Surgery, Plastic Surgery, clinical data, including gender, age, length of stay at the hospital, the underlying cause(s), number of debridement, predisposing factors, and surgical reconstructive data over 10 years were assessed and analyzed retrospectively. RESULTS:The mean age of the 35 patients was 58.14±12.71 years. Diabetes mellitus was present in 20 of the 35 (57.1%) patients. Twelve of the patients (34.2%) were hospitalized in the intensive care unit (ICU). Length of stay in the ICU was found to be significantly influenced by age, hematocrit level, FGSI and UFGSI (p=0.013, p=0.030 p=0.025 and p=0.002, respectively). CONCLUSION:Fournier's gangrene is a fulminant infection with a high mortality rate. Physical examination and anamnesis are quite important for the diagnosis of FG. DM is the most common comorbidity. Age, hematocrit level, FGSI and UFGSI scores affect the patients' length of stay in the ICU.

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Section: Discussionmentioning

confidence: 64%

Section: Resultsmentioning

confidence: 99%

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Fournier’s Gangrene: Five Years’ Experience from a Single Center in Turkey

Hatipoğlu¹

2020

Ulus Travma Acil Cerrahi Derg

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“…Fournier's gangrene is a rare but feared necrotizing fasciitis of the genitals and perineum associated with significant morbidity and mortality between 7% and 40% 1–3 . It is a polymicrobial infection spreading along subcutaneous and fascial planes 2 .…”

Section: Figurementioning

confidence: 99%

“…Fournier's gangrene is a rare but feared necrotizing fasciitis of the genitals and perineum associated with significant morbidity and mortality between 7% and 40%. [1][2][3] It is a polymicrobial infection spreading along subcutaneous and fascial planes. 2 Clinically, it can be difficult to diagnose, but due to its rapid progression, and requires immediate and aggressive surgical debridement.…”

mentioning

confidence: 99%

Sigmoid diverticulitis leading to Fournier's gangrene

Parkin

Acland

Ilie

et al. 2020

ANZ Journal of Surgery

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A prospective case series of Fournier's gangrene at a tertiary centre involving adjacent organs

David

Traeger

Kahokehr

et al. 2021

ANZ Journal of Surgery

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Background: Recent studies of patients with Fournier's gangrene (FG) highlight the importance of early surgical intervention in improving mortality rates. We prospectively determined subgroups of patients with FG at high risk of severe local morbidity. Methods: We prospectively evaluated all patients diagnosed with FG at a tertiary hospital (1 January 2018 to 1 January 2021). Data were collated on demographics, comorbidity, infection source, treatment and clinical outcomes. Results: We identified 14 consecutive male patients with a median (interquartile range) age of 57 (50-64) years. Most common risk factors were diabetes (n = 10, 71%) and obesity (n = 10, 71%). Median (range) HbA1c was 11.20 (7.5-15.3), and body mass index of 41.25 (23.7-70.0). Seven patients had adjacent organ involvement (AOI), involving the corporal bodies (57%) and testes (43%). The most common suspected source was dermatological (50%), followed by genitourinary (29%) and gastrointestinal (GI) (21%). Median (interquartile range) hospital length of stay (LOS) was 32 (8.5-30.75) days. Patients with AOI were more likely to have a suspected GI source, need mechanical ventilation (p = 0.023), a significantly longer LOS (p = 0.015) and time to wound closure (p = 0.04). Patients with suspected dermatological origin of infection, had a significantly lower rate of AOI (p = 0.029), mechanical ventilation (p = 0.029) and a shorter LOS (p = 0.035). Conclusion: In our prospective series, FG is associated with a high rate of AOI and suspected non-dermatological origin of infection, which confers significant perioperative morbidity including the need for mechanical ventilation, LOS and longer time from initial debridement to wound closure. †Statistics presented: n/n (%). ‡Fisher's exact test.

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Fournier's gangrene: not as lethal as previously thought? A case series

Abstract: While a prolonged admission and multiple operations are expected, early diagnosis and aggressive multimodal treatment may result in a significantly better survival outcome than those quoted in previous literature.

Cited by 12 publications

References 7 publications

Fournier’s Gangrene: Five Years’ Experience from a Single Center in Turkey

Fournier’s Gangrene: Five Years’ Experience from a Single Center in Turkey

Sigmoid diverticulitis leading to Fournier's gangrene

A prospective case series of Fournier's gangrene at a tertiary centre involving adjacent organs

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