2010
DOI: 10.1590/s0100-40422010000600025
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Fosfatos de cálcio de interesse biológico: importância como biomateriais, propriedades e métodos de obtenção de recobrimentos

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Cited by 56 publications
(75 citation statements)
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“…The apparent success of the ExO methodology comes from the reaction between cal-cium chloride and PBS salts at neutral pH, generating calcium phosphate precipitates (Rigo et al, 2007;Guastaldi and Aparecida, 2010). The precipitated nanocrystals adsorbed proteins (Figure 3) via interaction between the protein group (NH 4 + ) and the crystal group (PO 4 -) or complex formation between HA-Ca 2 + --OOC-protein keeping only the nucleic acids of the ground material in contact with organic phases of the extraction process.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…The apparent success of the ExO methodology comes from the reaction between cal-cium chloride and PBS salts at neutral pH, generating calcium phosphate precipitates (Rigo et al, 2007;Guastaldi and Aparecida, 2010). The precipitated nanocrystals adsorbed proteins (Figure 3) via interaction between the protein group (NH 4 + ) and the crystal group (PO 4 -) or complex formation between HA-Ca 2 + --OOC-protein keeping only the nucleic acids of the ground material in contact with organic phases of the extraction process.…”
Section: Resultsmentioning
confidence: 99%
“…The precipitated nanocrystals adsorbed proteins (Figure 3) via interaction between the protein group (NH 4 + ) and the crystal group (PO 4 -) or complex formation between HA-Ca 2 + --OOC-protein keeping only the nucleic acids of the ground material in contact with organic phases of the extraction process. The hydroxyapatite and octacalcic phosphate precipitates formed the cell debris, based on the principle underlying the use of silica beads for DNA (Rojas-Herrera et al, 2008); this idea is already used in HPLC (Guastaldi and Aparecida, 2010). Formation of these insoluble phosphates is similar to the biomimicking process proposed by Abe et al (1990).…”
Section: Resultsmentioning
confidence: 99%
“…Other nutrients such as proteins and vitamin C act directly in the synthesis of collagen, an important component in the skin structure. They act directly on the specific functions acquired by the several combinations of structural amino acids and on the formation of hydroxylases which transform lysine and proline, nutrients which are responsible for the synthesis of this collagen 30,31,34,39,40 .…”
Section: Discussionmentioning
confidence: 99%
“…No entanto, foram observadas algumas desvantagens com o uso deste método: restrição da utilização somente para substratos metálicos, utilização somente de HA como material de recobrimento devido aos demais fosfatos de cálcio produzirem estresse mecânico entre o recobrimento e o substrato [14].…”
Section: Plasma Sprayunclassified