Formulation Of Effervescent Tablet Of Temulawak Extract (Curcuma xanthorrhiza Roxb.) With Variation Of Stevia As Sweetener

Abstract

The effervescent tablet containing extract of temulawak (Curcuma xanthorrhiza Roxb.) with variation of stevia sweetener has been formulated using wet granulation method. This research aims to find the formulation of effervescent tablet of temulawak extract (Curcuma xanthorrhiza Roxb.) with the variation of stevia sweetener that meets the requirements of physical tablet test. The effervescent tablet formula was made in three formulas with the difference in the stevia content. Tests conducted include visual tests, uniformity test, hardness test, friability test, pH test and solubility test. Based on the test results on the physical properties of tablets, it is known that all the formula meets the physical test of tablets and the preferred formula is formula 3 with 4% of stevia.

Cinnamon and amylum mucilage alter the physicochemical, sensory, and antioxidant activity of Arthrospira platensis granules

“…The sweetener used is stevia sugar. The concentration of stevia sugar used is 4%, according to research by [10] stevia sugar of 4% is the most preferred concentration of panelists because it can mask the bitter taste. The filler material used is tapioca flour with a ratio of tapioca flour and water of 5:3.…”

Calcium Extract Characterization from Rajungan Crab Shell (Portunus pelagicus) and Bakau Crab Shell (Scylla serrata) using Calcination as Effervescent

“…Dextrin is a filler and protective agent for effervescent powders (Purwati et al, 2016). The sweetener in the formulation is a sweetener that is often used in pharmaceutical preparations, namely aspartame (Lynatra et al, 2018). The function of adding PVP to the formulation is as a binder (Putra et al, 2019).…”

Formulasi Sediaan Tablet Effervescent Ekstrak Herbal Meniran (Phyllantus niruri L) dengan Variasi Konsentrasi Sumber Asam dan Basa

“…Hasil pengujian berdasarkan tabel 3 ketiga formula memenuhi persyaratan uji kurang dari 20%. Hal ini sejalan dengan penelitian (Lynatra et al, 2018) formulasi tablet effervescent ekstrak temulawak dengan variasi pemanis stevia, diperoleh nilai kompresibilitas dengan rentang 12-16%. Nilai kompresibilitas dapat dipengaruhi oleh sudut diam, bentuk, kerapatan dan ukuran granul.…”

“…Waktu larut tablet effervescent dipengaruhi oleh kekerasan tablet dimana hasil penelitian pada F3 memiliki nilai kekerasan lebih rendah yaitu 6 kg menghasilkan waktu larut tercepat yaitu 01.56 menit. Hasil ini sejalan dengan penelitian (Lynatra et al, 2018) dengan formulasi tablet effervescent dari ekstrak temulawak pada F1 memiliki nilai kekerasan tablet terendah yaitu 5,17 kg menghasilkan waktu larut tercepat pula yaitu 02.37 menit.…”

“…Hal ini dikarenakan jumlah sumber asam dan sumber basa setara sehingga pH larutan mendekati netral. Hal ini sejalan dengan penelitian (Lynatra et al, 2018) formulasi tablet effervescent dari ekstrak temulawak didapatkan rentang pH tablet effervescent 5-6.…”