Formulation And Evaluation Of Hand Sanitizer Gel From Clove Flower Extract (Eugenia aromatica L.)

Abstract

Clove flower (Eugenia aromatica L.) is a plant from the Myrtaceae family, the compounds contained in clove flowers are flavonoids, tannins, alkaloids, and saponins that can function as antibacterial. In addition, clove flowers also function as analgesic, anti-inflammatory, antimicrobial, antiviral, antifungal, antiseptic, antispasmodic, antiemetic, stimulant, and local anesthetic. The purpose of this study was to determine does clove flower extract (Eugenia aromatica L.) could be used as a hand sanitizer gel preparation. Clove flower simplicia powder was extracted with ethanol 96% by maceration. The extract obtained was then screened for phytochemicals, then formulated in the form of a hand sanitizer gel, by adding clove flower extract to each formula with different concentrations. The clove flower extract concentrations used were 5%, 10%, and 15%. After the hand sanitizer gel preparation was formed, the clove flower extract was then tested for the stability of the gel preparation. The clove flower extract obtained was 116.4 grams of thick extract. The results of phytochemical screening of clove flower extract showed the presence of secondary metabolites, namely flavonoids, alkaloids, saponins and tannins. Based on the evaluation of the hand sanitizer gel preparation, clove extract showed that it was physically stable during storage. Based on the acceptability or liking test conducted on 20 respondents using a questionnaire sheet, the results showed that the respondents really liked the aroma of formula F3.

FORMULASI SEDIAAN GEL EKSTRAK KULIT BATANG ASAM KANDIS (Garcinia xanthochymus Hook.f. ex. Anderson) DAN UJI ANTIINFLAMASI TERHADAP TIKUS PUTIH JANTAN

“…Artinya bahwa gel ekstrak kulit buah asam kandis dengan konsentrasi 5%, 10%, dan 15% pH gel yang baik adalah pH yang hampir sama atau mendekati pH kulit yang berkisar antara 4,5-6,5. Apabila sediaan gel terlalu asam dari pH kulit dikhawatirkan akan mengiritasi kulit tetapi apabila terlalu basa maka kulit dikhawatirkan akan kering (Robiatun et al, 2022).…”

Antioxidant Activity of Fresh Decinte, Fresh Sari, and Fresh Ethanol Extract of Soursop (Annona muricata L.) Leaves Using DPPH Method

“…Phytochemical screening tests were carried out to determine the content of secondary metabolites in plants such as alkaloids, flavonoids, tannins/polyphenols, saponins, and steroids/terpenoids 10 . Generally, this class of secondary metabolites has antioxidant activity 11 .…”

Development of Clove (Syzygium aromaticum) and Cinnamon (Cinnamomum burmannii) Based Food Sanitizer

“…The extract-based sanitizer was prepared using the procedures by Chen et al (2021) and Robiatun et al (2022). The number of extracts added was 5 times the highest minimum fungicidal concentration (MFC) or MBC value, while the food sanitizer based was made according to the formulation listed in Table 1.…”

“…The physicochemical test covered the color, pH, solubility and stability of the water-distilled extract-based sanitizer (WDS) and ethanol extract sanitizer (EES) (Ningsih et al, 2017;Robiatun et al, 2022). The color of the sanitizers was measured using a Minolta chromameter and the pH was estimated using pH universal.…”

“…These microorganisms are responsible for food-borne diseases, specifically in fresh or minimally processed food. Clove extract showed superior antimicrobial stability upon storage, which is preferable as an active compound in food sanitizer (Robiatun et al, 2022).…”