Formulation and characterization of novel nanostructured lipid carriers made from beeswax, propolis wax and pomegranate seed oil

Soleimanian, Yasamin; Goli, Sayed Amir Hossein; Varshosaz, Jaleh; Sahafi, Sayed Mohammad

doi:10.1016/j.foodchem.2017.10.010

Cited by 111 publications

(101 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This could be probably due to more solubility of the encapsulation material in the liquid part of the lipid. Results in this study were consistent with results of other researchers (Kiani, Fathi, & Ghasemi, ; Soleimanian et al, ; Yuan, Wang, Ye, Tao, & Zhang, ).…”

Section: Resultssupporting

confidence: 93%

“…The same instrument/machine applied by the Helmholtz–Smoluchowski equation to convert/transform the specified particle electrophoretic dynamism into zeta average was used to determine the electrical charge of lipid nanoparticles in a capillary cell. Prior to analysis, the nanostructure lipid carrier samples were diluted 1:10 with a dilute phosphate buffer to elude multiple scattering effects (Nash & Haeger, ; Soleimanian, Hossein Goli, Varshosaz, & Sahafi, ).…”

Section: Methodsmentioning

confidence: 99%

“…Prior to analysis, the nanostructure lipid carrier samples were diluted 1:10 with a dilute phosphate buffer to TA B L E 1 Formulation composition (weight of emulsion) of nanostructure lipid carriers *For all formulation 2% Tween 80 were added. elude multiple scattering effects (Nash & Haeger, 1966;Soleimanian, Hossein Goli, Varshosaz, & Sahafi, 2018…”

Section: Dynamic Light Scatteringmentioning

confidence: 99%

See 2 more Smart Citations

Spanish olive leaf extract‐loaded nanostructured lipid carriers: Production and physicochemical characterization by Zetasizer, FT‐IR, DTA/TGA, FE‐SEM and XRD

Soleimanifard

Mahoonak

Sepahvand

et al. 2019

J Food Process Preserv

View full text Add to dashboard Cite

In this research, using ethanol/methanol/acetone‐water solvents and semipreparative high‐performance liquid chromatography, the phenolic compounds of the pure olive leaf were extracted. Then, the compounds were encapsulated using a proper lipid mixture and surfactant. For production of nanocarriers, a hot high‐shear homogenization method accompanied with ultrasonication techniques was applied. Next, the optimum nanocarrier was investigated in terms of zeta potential, morphology, thermal behavior, chemical interactions, and crystallinity structure. Results of dynamic light scattering showed that the optimum carrier had lower values of particle size and polydispersity index than the other carriers. Structural and thermal analyses exhibited that the crystalline state of the prepared oleuropein‐loaded nanocarrier was not highly ordered compared with the oleuropein‐free nanocarrier. The Fourier transform infrared spectroscopy analysis showed that oleuropein was successfully accommodated inside wall materials. The sensory analysis of mayonnaise sauce samples represented no significant difference between the mayonnaise sauce containing optimum nanocarriers and the control. Practical applications One of the aims of the application of nanocarriers in the food industry is to improve bioavailability, cover the undesirable odor, flavor, color, and improve solubility of some materials. Results of this work depicted that adding nanocarriers containing olive leaf extract powder as the source rich of oleuropein to the food, such as sauce, could improve the undesirable appearance, color, odor, and flavor of the extract powder (polyphenols such as oleuropein) and also enjoy high durability of antioxidant properties of the polyphenols existing in the nanocarrier. A practical opinion/idea is that encapsulation of olive leaf extract powder as nutraceutical component can be applied to nutritive and pharmaceutical industries as well as production of high‐quality products with whiteness, uniformity/homogeneity, appropriate flowability, and flavor properties. In other words, the results of the present study can be used to formulate appropriate NLC to deliver oleuropein and other nutraceuticals into foods and pharmaceutical products.

show abstract

Section: Resultssupporting

confidence: 93%

Section: Methodsmentioning

confidence: 99%

Section: Dynamic Light Scatteringmentioning

confidence: 99%

See 1 more Smart Citation

Spanish olive leaf extract‐loaded nanostructured lipid carriers: Production and physicochemical characterization by Zetasizer, FT‐IR, DTA/TGA, FE‐SEM and XRD

Soleimanifard

Mahoonak

Sepahvand

et al. 2019

J Food Process Preserv

View full text Add to dashboard Cite

show abstract

“…Nanostructured lipid carriers (NLCs) are delivery systems with less‐ordered crystalline structure, which consist of a binary mixture of a solid lipid together with a distinct liquid lipid primarily developed to circumvent the limitations of solid lipid nanoparticles (SLNs) . As second generation of SLN, the globule size of NLCs ranged 10–1000 nm and remained solid at room temperature with several advantages like bio‐compatible lipids utilization, avoidance of first pass metabolism via lymphatic transport and protection of drug moiety against biochemical degradation…”

Section: Recent Developments In Formulation Of Psomentioning

confidence: 99%

“…Soleimanian et al developed NLC with functional capability using beeswax, propolis wax and PSO via ultrasonication method. On the account of the above‐mentioned formulations, PSO could serve as oil phase with functional properties.…”

Section: Recent Developments In Formulation Of Psomentioning

confidence: 99%

Formulation of Pomegranate Seed Oil: A Promising Approach of Improving Stability and Health‐Promoting Properties

Adu‐Frimpong

Omari‐Siaw

Mukhtar

et al. 2018

Euro J Lipid Sci & Tech

View full text Add to dashboard Cite

Emerging evidence has suggested that nutraceutical ingredients like pomegranate seed oil (PSO) possesses health‐promoting effects in cell and animal models. However, these health benefits (anticancer, antioxidant, anti‐inflammatory, anti‐diabetic, and so on) are limited by low physicochemical stability, slow intestinal absorption, and rapid metabolism of PSO. In order to overcome these drawbacks, some carriers viz., nanoemulsion, encapsulation, and nanoparticles are developed recently. This paper assesses the chemical compositions and physicochemical properties of PSO, as well as biological activities and possible mechanisms. It also discusses the formulation of PSO for improved stability and health‐promoting activities. Practical Applications: This review highlights the prospects of PSO formulation. The relevance of this study is that the stability and biological properties of PSO could be enhanced through nanocarriers. A formulated PSO has a potential use in nutraceutical, functional foods, pharmaceutical and cosmetic industries. PSO, a source of various nutrients and antioxidants with immense benefits to human health is incorporated into nanocarriers such as microencapsulation, nanoemulsion and nanoparticle. This improved the health‐promoting benefits of the oil.

show abstract

Novel Nanostructured Lipid Carriers with Photoprotective Properties Made from Carnauba Wax, Beeswax, and Kenaf Seed Oil

Lee

Chu

Hasan

et al. 2019

J Americ Oil Chem Soc

View full text Add to dashboard Cite

This study was aimed to produce a stable kenaf seed oil-nanostructured lipid carrier (KSO-NLC) sunscreen, which can help in the photoprotective effect. The nanostructured lipid carrier (NLC) formulation was optimized and selected based on the results of mean particle size, polydispersity index (PDI), and storage stability of formulas at both chilled (4 AE 2 C) and room (25 AE 2 C) temperatures. Uvinul A plus B was added to KSO-NLC with the optimized formula (80% w/w aqueous phase, 20% w/w lipid phase, and 7% w/w of surfactants with a ratio of 70:15:15 of Tween 20: poloxamer 188: lecithin). The mean particle size distribution (224.73 AE 1.56 nm) and PDI (0.41 AE 0.01) of KSO-NLC were determined and were found to be stable against storage without creaming or phase separation. The 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging and 2,2 0 -Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical-scavenging activities of KSO-NLC were 5.43 AE 1.00 mg Trolox equiv. g −1 of NLC and 6.70 AE 0.31 mg Trolox equiv. g −1 of NLC, respectively. The Sun Protection Factor (SPF) of KSO-NLC, 41.38 AE 6.03 with a UVA/UVB ratio 0.64 AE 0.01, suggested a good photoprotective effect. The sustained release of Univul A plus B from KSO-NLC accompanied by its entrapment efficiency up to 64.09 AE 0.98% and drug loading (DL) of 32.05 AE 0.49% (maximum 50% DL capacity) proved that the degradation of the ultraviolet (UV) filter could be reduced. Therefore, the KSO-NLC sunscreen was a feasible solution for the photoprotective approach by using unconventional plant seed oil with a significant enhancement (P < 0.05) in many aspects compared to the formula without KSO incorporation. Keywords Particle size Á Polydispersity index (PDI) Á Uvinul a plus B Á Entrapment efficiency (EE) Á Drug loading (DL) J Am Oil Chem Soc (2019) 96: 201-211.

show abstract

Formulation and characterization of novel nanostructured lipid carriers made from beeswax, propolis wax and pomegranate seed oil

Cited by 111 publications

References 30 publications

Spanish olive leaf extract‐loaded nanostructured lipid carriers: Production and physicochemical characterization by Zetasizer, FT‐IR, DTA/TGA, FE‐SEM and XRD

Spanish olive leaf extract‐loaded nanostructured lipid carriers: Production and physicochemical characterization by Zetasizer, FT‐IR, DTA/TGA, FE‐SEM and XRD

Formulation of Pomegranate Seed Oil: A Promising Approach of Improving Stability and Health‐Promoting Properties

Novel Nanostructured Lipid Carriers with Photoprotective Properties Made from Carnauba Wax, Beeswax, and Kenaf Seed Oil

Contact Info

Product

Resources

About