Formation of Magnetite Nanoparticles at Low Temperature: From Superparamagnetic to Stable Single Domain Particles

Baumgartner, Jens; Bertinetti, Luca; Widdrat, Marc; Hirt, Ann M.; Faivre, Damien

doi:10.1371/journal.pone.0057070

Cited by 112 publications

(83 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…They can be handled by using an external magnetic field and thus directed to a specific area in the body where they then excrete the medicine, avoiding delivery to unwanted tissues. MNPs can be formed either from pure metals (cobalt, nickel, manganese and iron) or alloys and their oxides [32]. However, only the iron oxide MNPs have been approved for clinical use by the Food and Drug Administration due to their inherent properties [29].…”

Section: Antimicrobial Approaches Based On Nanotechnologymentioning

confidence: 99%

Magnetite Nanostructures as Novel Strategies for Anti-Infectious Therapy

2014

View full text Add to dashboard Cite

Abstract:This review highlights the current situation of antimicrobial resistance and the use of magnetic nanoparticles (MNPs) in developing novel routes for fighting infectious diseases. The most important two directions developed recently are: (i) improved delivery of antimicrobial compounds based on a drastic decrease of the minimal inhibition concentration (MIC) of the drug used independently; and (ii) inhibition of microbial attachment and biofilm development on coated medical surfaces. These new directions represent promising alternatives in the development of new strategies to eradicate and prevent microbial infections that involve resistant and biofilm-embedded bacteria. Recent promising applications of MNPs, as the development of delivery nanocarriers and improved nanovehicles for the therapy of different diseases are discussed, together with the mechanisms of microbial inhibition.

show abstract

Section: Antimicrobial Approaches Based On Nanotechnologymentioning

confidence: 99%

Magnetite Nanostructures as Novel Strategies for Anti-Infectious Therapy

2014

View full text Add to dashboard Cite

show abstract

“…HRTEM analysis has produced a wealth of knowledge about the iron oxide formation in biological and synthetic systems alike. The "freeze and look" approach proved a very effective tool for evaluation of the complex synthetic pathways, notably the biomimetic formation of the nanoscale magnetite [165][166][167][168][170][171][172][173][174][175][176]. Importantly, the mechanism of biomimetic iron oxide formation remains unclear, largely because the analysis of the formed biomimetic solid is carried out either postsynthesis [6,21,22,34,44,78,177] or is performed on aliquots sampled during different stages of the growth process [165,166,171,173,[178][179][180][181][182].…”

Section: The Near In Situ Approachmentioning

confidence: 99%

TEM and Associated Techniques

Prozorov

2016

Iron Oxides

View full text Add to dashboard Cite

Common Abbreviations ADF annular dark field AEM analytical electron microscopy BF bright field CCD charge-coupled device CCF cross-correlated function DF dark field DP diffraction pattern EELS electron energy-loss spectrometry EFI energy-filtered imaging EFTEM energy-filtered transmission electron microscopy EH electron holography ELNES energy-loss near-edge structure ETEM environmental transmission electron microscopy eV electron volt EXAFS extended X-ray absorption fine structure FEG field-emission electron gun FFT fast Fourier transform FIB focused ion beam FM fluorescence microscopy GIF Gatan Imaging filter TM HAADF high-angle annular dark field HRTEM high-resolution transmission electron microscopy HV high vacuum LC liquid cell MC minimum contrast MS multiple scattering MV megavolt PB phase boundary P/B peak to background ratio Iron Oxides: From Nature to Applications, First Edition. Edited by Damien Faivre.

show abstract

“…Nanostructures exhibit unique physicochemical and biological properties, which makes them a favorable material for biomedical applications. 26,29 Nanoscale structures, or nanosized structures, can be used to carry drugs such as liposomes, synthetic and natural polymers, inorganic and metal NPs, dendrimers, silica, and carbon materials, as well as magnetic NPs (MNPs) 30,31 ( Figure 2). …”

mentioning

confidence: 99%

Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?

Voltan¹,

Quindós²,

Alarcón³

et al. 2016

IJN

View full text Add to dashboard Cite

Invasive mycoses are a major problem for immunocompromised individuals and patients in intensive care units. Morbidity and mortality rates of these infections are high because of late diagnosis and delayed treatment. Moreover, the number of available antifungal agents is low, and there are problems with toxicity and resistance. Alternatives for treating invasive fungal infections are necessary. Nanostructured systems could be excellent carriers for antifungal drugs, reducing toxicity and targeting their action. The use of nanostructured systems for antifungal therapy began in the 1990s, with the appearance of lipid formulations of amphotericin B. This review encompasses different antifungal drug delivery systems, such as liposomes, carriers based on solid lipids and nanostructure lipids, polymeric nanoparticles, dendrimers, and others. All these delivery systems have advantages and disadvantages. Main advantages are the improvement in the antifungal properties, such as bioavailability, reduction in toxicity, and target tissue, which facilitates innovative therapeutic techniques. Conversely, a major disadvantage is the high cost of production. In the near future, the use of nanosystems for drug delivery strategies can be used for delivering peptides, including mucoadhesive systems for the treatment of oral and vaginal candidiasis.

show abstract

Formation of Magnetite Nanoparticles at Low Temperature: From Superparamagnetic to Stable Single Domain Particles

Cited by 112 publications

References 46 publications

Magnetite Nanostructures as Novel Strategies for Anti-Infectious Therapy

Magnetite Nanostructures as Novel Strategies for Anti-Infectious Therapy

TEM and Associated Techniques

Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?

Contact Info

Product

Resources

About