Forecasting the Effects of the New SARS-CoV-2 Variant in Europe

Area, Iván; Nieto, Juan J.

doi:10.1155/2021/5553240

Cited by 4 publications

(4 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This population is also the one with the highest risk of dying-70% of the deaths from COVID in the Autonomous Community were over 80 years old. These data do not differ from other epidemiological studies published to date [20,23].…”

Section: Discussionsupporting

confidence: 61%

See 1 more Smart Citation

One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves

Area

Lorenzo

Marcos

et al. 2021

IJERPH

Self Cite

View full text Add to dashboard Cite

In this work we look at the past in order to analyze four key variables after one year of the COVID-19 pandemic in Galicia (NW Spain): new infected, hospital admissions, intensive care unit admissions and deceased. The analysis is presented by age group, comparing at each stage the percentage of the corresponding group with its representation in the society. The time period analyzed covers 1 March 2020 to 1 April 2021, and includes the influence of the B.1.1.7 lineage of COVID-19 which in April 2021 was behind 90% of new cases in Galicia. It is numerically shown how the pandemic affects the age groups 80+, 70+ and 60+, and therefore we give information about how the vaccination process could be scheduled and hints at why the pandemic had different effects in different territories.

show abstract

Section: Discussionsupporting

confidence: 61%

“…The second corresponds to the full period of pandemic. Finally, we have performed a detailed analysis of 80+ age group's data evolution, from 1 January 2021 to 1 April 2021, as in the last days of December 2020 vaccination started in this group, and the first B.1.1.7 lineage infection (British strain) was detected in Galicia [20].…”

Section: Methodsmentioning

confidence: 99%

One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves

Area

Lorenzo

Marcos

et al. 2021

IJERPH

Self Cite

View full text Add to dashboard Cite

show abstract

“…In our study, we have evaluated the commercialized screening kit that is mainly utilized. The ID Solution kit, performed prospectively in routine, has quickly highlighted the predominance of the UK variant, the most frequent variant currently isolated in France and Europe [ 13 , 17 , 18 ].…”

Section: Discussionmentioning

confidence: 99%

Limitation of Screening of Different Variants of SARS-CoV-2 by RT-PCR

et al. 2021

View full text Add to dashboard Cite

Since January 2021, the diffusion of the most propagated SARS-CoV-2 variants in France (UK variant 20I/501Y.V1 (lineage B.1.1.7), 20H/H501Y.V2 (lineage B.1.351) and 20J/H501Y.V3 (lineage P.1)) were urgently screened, needing a surveillance with an RT-PCR screening assay. In this study, we evaluated one RT-PCR kit for this screening (ID SARS-CoV-2/UK/SA Variant Triplex®, ID Solutions, Grabels, France) on 2207 nasopharyngeal samples that were positive for SARS-CoV-2. Using ID Solutions kit, 4.1% (92/2207) of samples were suspected to belonged to B.1.351 or P.1 variants. Next-generation sequencing that was performed on 67.4% (62/92) of these samples confirmed the presence of a B.1.351 variant in only 75.8% of the samples (47/62). Thirteen samples belonged to the UK variant (B.1.1.7), and two to A.27 with N501Y mutation. The thirteen with the UK variant presented one mutation in the S-gene, near the ΔH69/ΔV70 deletion (S71F or A67S), which impacted the detection of ΔH69/ΔV70 deletion. Using another screening kit (PKampVariantDetect SARS-CoV-2 RT-PCR combination 1 and 3® PerkinElmer, Waltham, MA, USA) on the misidentified samples, we observed that the two mutations, S71F or A67S, did not impact the detection of the UK variant. In conclusion, this study highlights the limitations of the screening strategy based on the detection of few mutations/deletions as well as it not being able to follow the virus evolution.

show abstract

“…Medical bureaucracies have established many “front lines” in the battle against COVID-19 that people's lives have been changed because of the dangers of a pandemic. Additionally, COVID-19 has lots of new COVID-19 variants, which characteristic faster and dangerous (Area and Nieto, 2021; Bindayna and Crinion, 2021). The health-care system has shown an overload not only in the emergency resuscitation sector with doctors and nurses (Lapostolle et al , 2020; Ouyang, 2020) but also medical device industry.…”

Section: Introductionmentioning

confidence: 99%

Linear regression model and least square method for experimental identification of AMBU bag in simple ventilator

Truong

Huynh

Duong

et al. 2022

IJIUS

View full text Add to dashboard Cite

PurposeIn the COVID-19 outbreak periods, people's life has been deranged, leading to disrupt the world. Firstly, the number of deaths is growing and has the potential to surpass the highest level at any time. Secondly, the pandemic broke many countries' fortified lines of epidemic prevention and gave people a more honest view of its seriousness. Finally, the pandemic has an impact on life, and the economy led to a shortage in medical, including a lack of clinicians, facilities and medical equipment. One of those, a simple ventilator is a necessary piece of medical equipment since it might be useful for a COVID-19 patient's treatment. In some cases, the COVID-19 patients require to be treated by modern ventilators to reduce lung damage. Therefore, the addition of simple ventilators is a necessity to relieve high work pressure on medical bureaucracies. Some low-income countries aim to build a simple ventilator for primary care and palliative care using locally accessible and low-cost components. One of the simple principles for producing airflow is to squeeze an artificial manual breathing unit (AMBU) iterative with grippers, which imitates the motion of human fingers. Unfortunately, the squeezing angle of grippers is not proportional to the exhaust air volume from the AMBU bag. This paper aims to model the AMBU bag by a mathematical equation that enables to implement on a simple controller to operate a bag-valve-mask (BVM) ventilator with high accuracy performance.Design/methodology/approachThis paper provides a curvature function to estimate the air volume exhausting from the AMBU bag. Since the determination of the curvature function is sophisticated, the coefficients of the curvature function are approximated by a quadratic function through the experimental identification method. To obtain the high accuracy performance, a linear regression model and a least square method are employed to investigate the characteristic of the BVM ventilator's grippers angle with respect to the airflow volume produced by the AMBU bag.FindingsThis paper investigates the correlation between the exhausting airflow of the AMBU bag and the grippers angle of the BVM ventilator.Originality/valueThe experimental results validated that the regression model of the characteristic of the exhausting airflow of the AMBU bag with respect to the grippers' angle has been fitted with a coefficient over 98% within the range of 350–750 ml.

show abstract

Forecasting the Effects of the New SARS-CoV-2 Variant in Europe

Cited by 4 publications

References 17 publications

One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves

One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves

Limitation of Screening of Different Variants of SARS-CoV-2 by RT-PCR

Linear regression model and least square method for experimental identification of AMBU bag in simple ventilator

Contact Info

Product

Resources

About