Forced oscillation measurements do not affect upper airway muscle tone or sleep in clinical studies

Badia, Joan R.; Farré, Ramón; Rigau, Jordi; Uribe, Mireia; Navajas, Daniel; Montserrat, Josep M.

doi:10.1183/09031936.01.00085001

Cited by 19 publications

(6 citation statements)

References 22 publications

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“…Although initial data showed that oscillometry was able to distinguish OSA patients from healthy adults [181], its application for simplified diagnosis has not yet been implemented in routine clinical practice. However, oscillometry is useful for monitoring upper airway collapse during sleep [183][184][185]. Oscillometry also provides insight into how airway resistance is normalised by application of continuous positive airway pressure (CPAP) [186], and how sleep apnoea and asthma may interact to worsen airway obstruction [187].…”

Section: Sleep Apnoeamentioning

confidence: 99%

Clinical significance and applications of oscillometry

Kaminsky

Simpson

Berger³

et al. 2022

Eur Respir Rev

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Recently, “Technical standards for respiratory oscillometry” was published, which reviewed the physiological basis of oscillometric measures and detailed the technical factors related to equipment and test performance, quality assurance and reporting of results. Here we present a review of the clinical significance and applications of oscillometry. We briefly review the physiological principles of oscillometry and the basics of oscillometry interpretation, and then describe what is currently known about oscillometry in its role as a sensitive measure of airway resistance, bronchodilator responsiveness and bronchial challenge testing, and response to medical therapy, particularly in asthma and COPD. The technique may have unique advantages in situations where spirometry and other lung function tests are not suitable, such as in infants, neuromuscular disease, sleep apnoea and critical care. Other potential applications include detection of bronchiolitis obliterans, vocal cord dysfunction and the effects of environmental exposures. However, despite great promise as a useful clinical tool, we identify a number of areas in which more evidence of clinical utility is needed before oscillometry becomes routinely used for diagnosing or monitoring respiratory disease.

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Section: Sleep Apnoeamentioning

confidence: 99%

Clinical significance and applications of oscillometry

Kaminsky

Simpson

Berger³

et al. 2022

Eur Respir Rev

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“…Two other methods that have been extensively investigated in this context are the recording of pressure at the airway opening, mostly via nasal cannula (5)(6)(7)(8), and the measurement of signals related to mechanical respiratory input impedance by the forced oscillation technique (FOT) (9)(10)(11)(12)(13)(14)(15)(16)(17)(18). Both methods are highly sensitive with respect to the detection of disturbed breathing during sleep (5,12,13,16).…”

Section: Abstract: Sleep-disordered Breathing; Diagnosis; Classificatmentioning

confidence: 99%

Diagnosis of Sleep Apnea by Automatic Analysis of Nasal Pressure and Forced Oscillation Impedance

Steltner¹,

Staats²,

Timmer³

et al. 2002

Am J Respir Crit Care Med

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Detecting and differentiating central and obstructive respiratory events is an important aspect of the diagnosis of sleep-related breathing disorders with respect to the choice of an appropriate treatment. The purpose of this study was to evaluate the performance of a new algorithm for automated detection and classification of apneas and hypopneas, compared with visual analysis of standard polysomnographic signals. The algorithm is based on time series analysis of nasal mask pressure and a forced oscillation signal related to mechanical respiratory input impedance, measured at a frequency of 20 Hz throughout the night. The method was applied to all-night measurements on 19 subjects. Two experts in sleep medicine independently scored the corresponding simultaneously recorded polysomnographic signals. Evaluating the agreement between two scorers by a weighted kappa statistic on a second-by-second basis, we found that inter-expert variability and the discrepancy between automatic analysis and visual analysis performed by an expert were not significantly different. Implementation of this algorithm in a device for home monitoring of breathing during sleep might aid in the differential diagnosis of sleep-related breathing disorders and/or as a means for follow-up and treatment control.

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“…The rationale for avoiding the measurement of transpulmonary pressure is that the inspiratory muscles do not contribute towards generating oscillatory flow at the high FOT frequency (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20) whereas, in the case of airway closure, FOT measures the effective impedance of the airway segment from the mask to the collapse site. The technique allows a continuous, automatic and real-time monitoring of airway impedance [48,49] without disturbing the patient9s sleep [50]. Figure 9 is an example of the signals recorded when FOT was applied to assess airway obstruction in a patient with SAHS during CPAP.…”

Section: Forced Oscillation Techniquementioning

confidence: 99%

Noninvasive monitoring of respiratory mechanics during sleep

Farré¹,

Montserrat

Navajas³

2004

European Respiratory Journal

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The sleep apnoea-hypopnoea syndrome is characterised by recurrent obstructions of the upper airway, resulting in sleep disruption and arterial oxygen desaturations. Noninvasive assessment of respiratory mechanics during sleep is helpful in facilitating the diagnosis and treatment of patients with sleep apnoea-hypopnoea syndrome. This series summarises the different tools that are currently available to noninvasively assess respiratory mechanics during sleep breathing disturbances. These techniques are classified according to the main variable monitored: ventilation, breathing effort or airway obstruction. Changes in patient ventilation are assessed by recording flow or volume signals by means of pneumotachographs, thermistors or thermocouples, nasal prongs or thoraco-abdominal bands. Common tools to noninvasively assess breathing efforts are the thoraco-abdominal bands and the pulse transit time technique. Upper airway obstruction is noninvasively characterised by its upstream resistance and its critical pressure or by means of the forced oscillation technique. Given the technical and practical limitations of each technique, combining different tools improves the reliability and robustness of patient assessment during sleep.

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Forced oscillation measurements do not affect upper airway muscle tone or sleep in clinical studies

Cited by 19 publications

References 22 publications

Clinical significance and applications of oscillometry

Clinical significance and applications of oscillometry

Diagnosis of Sleep Apnea by Automatic Analysis of Nasal Pressure and Forced Oscillation Impedance

Noninvasive monitoring of respiratory mechanics during sleep

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