Force fluctuations during the Maximum Isometric Voluntary Contraction of the quadriceps femoris in haemophilic patients

Abstract

In the general population, the degenerative processes in joints are directly related to adult age, and osteoarthrosis represents the most frequent musculoskeletal alteration. In the haemophilic patient, the degenerative processes in the joint begin at very early ages, and are directly related to musculoskeletal bleeding episodes, which are occasionally subclinical and constitute haemophilic arthropathy. In the haemophilic patient, arthropathy constitutes the most frequent, severe and disabling pathology, and its assessment includes muscular force-related parameters. We have studied the value of Maximum Isometric Voluntary Contraction in the quadriceps femoris of 46 subjects, 28 haemophiliacs (16 severe, eight moderate and four mild) and 18 healthy individuals with a view to establishing appropriate values of force and to restoring physical therapy recommendations. The maximum force values were significantly greater (P < 0.001) in the healthy individuals group. The mild haemophiliacs group also presented significant differences of force (P < 0.05) in relation to the severe and moderate haemophilic patient groups. The mild and severe haemophilia patients presented greater fluctuations of force (P < 0.001) than the control group, the haemophilia group have a minor skill to produce constant force. The seriousness of the arthropathy in the knee is directly related to diminished values of maximum force. Our work evidences that patients with severe haemophilia present a greater degree of arthropathy in relation to moderate and mild haemophilia patients. Haemophilic arthropathy is associated with muscular atrophy and strength deficit. In haemophilic patients, the deficit of maximum force and the presence of fluctuations may suggest an increased risk of bleeding during physical activities and the need to programme specific physical therapy guidelines which increase muscular power through resistance training.

Hemofilia: ejercicio y deporte

“…Actualmente podemos decir que, en general, la condición física del paciente hemofílico adulto es baja, ya que hay estudios que muestran valores inferiores de resistencia aeróbica 49 , fuerza 37,50,51 , propiocepción y equilibrio 50,52,53 , respecto a los encontrados en sus pares sanos.…”

Effect of Using Treadmill Exercise on Mobility Skills in Hemophilic Children

“…Hemophilic present a decrease of proprioception of joint which can provoke alterations in basic force development pattern. Likewise, stability is also impeded in certain positions of dynamic balance [4]. Independent mobility is vital for activity, participation, and self-sufficiency, reducing the dependence on caregivers and the environment.…”

“…Exercises that improve balance and coordination are vital to any rehabilitation program [4]. So, the purpose of this study was to determinate the effect of using treadmill exercise to improve mobility skills during walking in hemophilic children.…”

Şiddetli Hemofili A Hastalarında Sınırlanmış Eklem Açıklığı ile İlişkili Atrofik Kaslarda Su İçi Egzersizlerin Etkisi: Bir Pilot Çalışma

“…Muscle atrophy and loss of strength were among the problems encountered in later stages of the disorder. Today, based on the guideline determined by the World Federation of Hemophilia, patients are encourage to increase muscle strength and protect range of motion 4,5,6,9 . Water exercise is the most highly recommended sport for haemophiliac patients in their daily life 8 .…”