Food selection based on high total antioxidant capacity improves endothelial function in a low cardiovascular risk population

Franzini, Laura; Ardigò, Diego; Valtueña, Silvia; Pellegrini, Nicoletta; Rio, Daniele Del; Bianchi, Marta; Scazzina, Francesca; Piatti, Pier Marco; Brighenti, Furio; Zavaroni, Ivana

doi:10.1016/j.numecd.2010.04.001

Cited by 87 publications

(48 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A higher proportion of MUFAs reduce the susceptibility of cholesterol molecules to oxidation (34)(35)(36). Free radicals can react with nitric oxide to produce peroxynitrite, thereby diminishing its vasodilatory effects (37). Antioxidants may inhibit the freeradical damage that can initiate and progress atherosclerosis, thereby resulting in a progressive loss of endothelial function (38).…”

Section: Discussionmentioning

confidence: 99%

A Mediterranean diet lowers blood pressure and improves endothelial function: results from the MedLey randomized intervention trial ,

Davis

Hodgson

Woodman

et al. 2017

The American Journal of Clinical Nutrition

147

118

View full text Add to dashboard Cite

Background: The consumption of a Mediterranean diet (MedDiet) is associated with a lower risk of cardiovascular disease. However, its impact on blood pressure and endothelial function is not clear. Objective: We sought to determine the effects of adhering to the consumption of a MedDiet for 6 mo on blood pressure and endothelial function in older, healthy Australians. Design: A total of 166 men and women aged .64 y were allocated via minimization to consume either a MedDiet (n = 85) or their habitual diet (HabDiet; control: n = 81) for 6 mo. The MedDiet comprised mainly plant foods, abundant extra-virgin olive oil, and minimal red meat and processed foods. A total of 152 participants commenced the study, and 137 subjects completed the study. Home blood pressure was measured on 5 consecutive days at baseline (n = 149) and at 3 and 6 mo. Endothelial function (n = 82) was assessed by flow-meditated dilatation (FMD) at baseline and 6 mo. Dietary intake was monitored with the use of 3-d weighed food records. Data were analyzed with the use of linear mixed-effects models to determine adjusted between-group differences. Results: The MedDiet adherence score increased significantly in the MedDiet group but not in the HabDiet group (P , 0.001). The MedDiet, compared with the HabDiet, resulted in lower systolic blood pressure (P-diet 3 time interaction = 0.02) [mean: 21.3 mm Hg (95% CI: 22.2, 20.3 mm Hg; P = 0.008) at 3 mo and 21.1 mm Hg (95% CI: 22.0, 20.1 mm Hg; P = 0.03) at 6 mo]. At 6 mo, the percentage of FMD was higher by 1.3% (95% CI: 0.2%, 2.4%; P = 0.026) in the MedDiet group. Conclusion: Australian men and women who consumed a MedDiet for 6 mo had small but significantly lower systolic blood pressure and improved endothelial function. This trial was registered at www.anzctr.org.au as ACTRN12613000602729.Am J Clin Nutr 2017;105:1305-13.

show abstract

Section: Discussionmentioning

confidence: 99%

A Mediterranean diet lowers blood pressure and improves endothelial function: results from the MedLey randomized intervention trial ,

Davis

Hodgson

Woodman

et al. 2017

The American Journal of Clinical Nutrition

147

118

View full text Add to dashboard Cite

show abstract

“…Modifying antioxidant intake by selecting foods based on their TAC could lead to a decreased risk of chronic diseases such as cancer (32,33). So, beyond the common recommendations regarding adherence to Mediterranean-style dietary patterns, selection of food items with a higher antioxidant load should also be recommended.…”

Section: Discussionmentioning

confidence: 99%

Dietary total antioxidant capacity and the risk of breast cancer: a case–control study

Karimi

Bahadoran

Abedini

et al. 2015

Easter Mediterr Health J

View full text Add to dashboard Cite

There is growing evidence that dietary antioxidants may have favourable effects in reducing cancer risk. In a case-control study we investigated the association of dietary total antioxidant capacity (TAC) and risk of breast cancer. Sociodemographic data, medical history and anthropometric measurements were collected from 275 women (100 breast cancer cases & 175 controls). Participants' usual dietary intake was measured using a validated semi-quantitative food frequency questionnaire and their dietary TAC was estimated. An inverse, but non-significant, association was observed between dietary TAC and breast cancer risk. Multiple logistic regression models based on TAC of individual food groups showed that consumption of fruits and vegetables with higher TAC (μmolTE/100 g) was associated with a significantly decreased risk of breast cancer. Our study supports a protective effect of dietary antioxidants in relation to breast cancer risk. Food selection based on TAC of foods may be an effective strategy to modify the risk of cancer. ‫وشواهد‬

show abstract

“…The available studies report an increased intake of selected food groups which increase the antioxidative potential of a diet and have a protective effect in the case of cardiovascular diseases [Franzini et al, 2012]. The meta-analysis published in 2014 revealed that an increase in the intake of flavo- noids by 500 mg/day was related to a 5% reduction of type 2 diabetes risk [Liu et al, 2014].…”

Section: Discussionmentioning

confidence: 99%

Total Antioxidant Capacity and Its Dietary Sources and Seasonal Variability in Diets of Women with Different Physical Activity Levels

Człapka-Matyasik¹,

Ast²

2014

Pol. J. Food Nutr. Sci.

View full text Add to dashboard Cite

Key words: ORAC, seasonal dietary intake, physical activity level, womenIncreased physical activity induces oxidative stress and utilization of dietary antioxidants. Information on dietary sources of antioxidants in diets are limited.We aimed to analyse the antioxidant potential, seasonal variation and dietary sources in the diets of women exercising and not exercising regularly. We studied 48 women: 25 regularly exercising (FIT) and 23 not exercising regularly (NFIT). 192 seasonal recalls were collected regarding the consumption of dietary sources of antioxidant compounds in spring, summer, autumn and winter. A food frequency questionnaire was used. For each season, the total density of the antioxidant diet (Q-ORAC in μmolTE/1000kcal) was calculated.The main sources of antioxidants in women's diets (FIT+NFIT) were fruit (32.1% of total supply), vegetables (11.5%), tea (9.3%), dark chocolate (5.7%), and sweets in total (1.9%) and red wine (1.1%). The Q-ORAC of women's diets (FIT+NFIT) significantly depended on the season (p<0.001) and were highest in the summer (23444 μmolTE/1000 kcal) and lowest in the spring (13978 μmolTE/1000 kcal). Higher differences in the Q-ORAC between seasons were observed in FIT women (Q-ORAC quotients from 0.8 to 1.9) than NFIT women (from 0.9 to 1.2). The Q-ORAC of FIT and NFIT women diet did not differ significantly in any season or average per year (18078 vs. 18775 μmolTE/1000 kcal, respectively; p>0.05).The total antioxidant density of women diets and consumption of dietary sources of antioxidants was not related to their physical activity. All of the women were characterised by seasonal variation in consumption, which was higher in active than inactive women. Unauthenticated Download Date | 5/8/18 6:45 AM

show abstract

Food selection based on high total antioxidant capacity improves endothelial function in a low cardiovascular risk population

Cited by 87 publications

References 38 publications

A Mediterranean diet lowers blood pressure and improves endothelial function: results from the MedLey randomized intervention trial ,

A Mediterranean diet lowers blood pressure and improves endothelial function: results from the MedLey randomized intervention trial ,

Dietary total antioxidant capacity and the risk of breast cancer: a case–control study

Total Antioxidant Capacity and Its Dietary Sources and Seasonal Variability in Diets of Women with Different Physical Activity Levels

Contact Info

Product

Resources

About