Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and ΔFosB expression in the nucleus accumbens of the rat

Stamp, Jennifer A.; Mashoodh, Rahia; Kampen, Jackalina M. Van; Robertson, Harold A.

doi:10.1016/j.brainres.2008.02.019

Cited by 50 publications

(48 citation statements)

References 40 publications

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“…Most studies on FR have shown that a reduction in the caloric intake is accompanied by an increase in the serum levels of corticosterone [10][11][12][13] , a body homeostatic response to the need for enhanced glicogenolysis. In FR rats, we observed almost a 100% increase in the blood content of corticosterone.…”

Section: Resultsmentioning

confidence: 99%

“…Restriction of caloric intake has been associated with an increase in the peak concentration of plasma corticosterone [10][11][12][13] . Moreover, it has been suggested that stress-induced elevations in glucocorticoid levels modulate hippocampal plasticity according to an inverted U-shaped function, with a moderate amount of circulating glucocorticoid-facilitating LTP expression, whereas higher glucocorticoid concentration impairing synaptic plasticity 40 .…”

Section: Discussionmentioning

confidence: 99%

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Food restriction enhances visual cortex plasticity in adulthood

Spolidoro¹,

Baroncelli²,

Putignano

et al. 2011

Nat Commun

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neural circuits display a heightened sensitivity to external stimuli during well-established windows in early postnatal life. After the end of these critical periods, brain plasticity dramatically wanes. The visual system is one of the paradigmatic models for studying experiencedependent plasticity. Here we show that food restriction can be used as a strategy to restore plasticity in the adult visual cortex of rats. A short period of food restriction in adulthood is able both to reinstate ocular dominance plasticity and promote recovery from amblyopia. These effects are accompanied by a reduction of intracortical inhibition without modulation of brainderived neurotrophic factor expression or extracellular matrix structure. our results suggest that food restriction could be investigated as a potential way of modulating plasticity.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Food restriction enhances visual cortex plasticity in adulthood

Spolidoro¹,

Baroncelli²,

Putignano

et al. 2011

Nat Commun

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“…Indeed, eating of high calorie food is known to counteract some effects of stress, probably via the same mechanism as in alcoholics (Kiefer and Grosshans, 2009). Chronic stress has been known to potentiate addictive behaviors in both human addicts and experimental animals (Stamp et al, 2008). By stimulating central reward pathways, high levels of corticosterone (the main GC in rodents) can reduce the aversiveness of the stressor (Piazza and Le Moal, 1997).…”

Section: Q4mentioning

confidence: 99%

Food-intake regulation during stress by the hypothalamo-pituitary-adrenal axis

Бажан¹,

Zelena²

2013

Brain Research Bulletin

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a b s t r a c tThe prevalence of obesity is increasing worldwide with serious consequences such as diabetes mellitus type 2 and cardiovascular diseases. Emotional stress is considered to be one of the main reasons of obesity development in humans. However, there are some contradictory results, which should be addressed. First of all stress induces anorexia, but not overeating in laboratory animals. Glucocorticoids, the effector molecules of the hypothalamo-pituitary-adrenocortical (HPA) axis stimulate and stress inhibits food intake. It is also not clear if stress is diabetogenic or an antidiabetogenic factor. The review will discusses these issues and the involvement of the whole HPA axis and its separate molecules (glucocorticoids, adrenocorticotropin, corticotropin-releasing hormone) in food intake regulation under stress.

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“…With respect to cocaine selfadministration, studies in outbred male rats have shown no reliable differences in individualcompared to pair-or group-housed peers [81,82]. In addition, although caloric restriction to 90% body weight can enhance initial locomotor responses to cocaine injections in adult outbred rats, this effect is not sustained after repeated exposure to cocaine [83]. Food restriction during adolescence in the current study likely did not impact cocaine responses during adulthood, as the cocaine self-administration training sessions began 22 days after a return to ad libitum feeding and lasted for several weeks before testing began.…”

Section: Discussionmentioning

confidence: 99%