Food and Fiber Animal Transfusion Medicine

Credille, Brent; Epstein, Kira L.

doi:10.1002/9781118933053.ch23

Cited by 3 publications

(3 citation statements)

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“…To compensate for the lack of erythrocytes, whole blood from a healthy donor animal can be transfused into the anaemic animal. From a healthy llama or alpaca, 20% of the circulating blood volume or 1.6% of the body weight can be taken for transfusion (Credille and Epstein 2016 ). Whitehead ( 2013 ) suggests transfusion of a single unit of 450 mL of blood from a healthy donor with a PCV between 0.24 and 0.28 l/l.…”

Section: Blood Transfusionmentioning

confidence: 99%

Section: Blood Transfusionmentioning

confidence: 99%

“…A practical solution is a blood transfusion bag in which the donor animal’s blood is collected, mixed with anticoagulants, and then administered intravenously to the anaemic animal (Credille and Epstein 2016 ; Wittek and Franz 2021 ). Blood transfusion should always be preceded by crossmatching of the donor and recipient to minimise the risk of transfusion reaction (Credille and Epstein 2016 ). To date, only little information is available on the blood groups of SACs (Penedo et al 1988 ), but according to Fowler and Bravo ( 2010 ), transfusion blood between different camelid species seems possible.…”

Section: Blood Transfusionmentioning

confidence: 99%

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Anaemia in South American camelids – an overview of clinical and laboratory diagnostics

Wagener,

Marahrens,

Ganter

2023

Vet Res Commun

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South American camelids (SACs) play an increasing role in veterinary care in Europe. Many alpacas or llamas presented to veterinarians suffer from anaemia, regularly with a packed cell volume (PCV) below 0.10 l/l, which is a life-threatening condition for the animals. This review article presents clinical and laboratory diagnostic tools for the diagnosis of anaemia in SACs. Clinical identification of anaemic animals can be performed by assessing the FAMACHA© score and the Body Condition Score (BCS), since anaemia in alpacas and llamas correlates with pale mucous membranes and a lowered BCS. Haematological examination of a blood sample can provide a more differentiated diagnosis of anaemia in SACs. A common finding is regenerative anaemia with an increased number of reticulocytes that is often caused by blood loss due to Haemonchus contortus. Changes in a blood smear from an alpaca or llama with regenerative anaemia may include normoblasts (nucleated red blood cells), anisocytosis, poikilocytosis, polychromasia, Howell-Jolly bodies or basophilic stippling. Furthermore, non-regenerative anaemia, often caused by trace element deficiency or cachexia, can also occur.

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Section: Blood Transfusionmentioning

confidence: 99%

Section: Blood Transfusionmentioning

confidence: 99%

Section: Blood Transfusionmentioning

confidence: 99%

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Anaemia in South American camelids – an overview of clinical and laboratory diagnostics

Wagener,

Marahrens,

Ganter

2023

Vet Res Commun

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Blood, Lymph, and Immune Systems

2022

Goat Medicine

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ABO blood type and risk of porcine bioprosthetic aortic valve degeneration: SWEDEHEART observational cohort study

Persson

Edgren

Dalén³

et al. 2019

BMJ Open

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ObjectiveBlood type A antigen on porcine aortic bioprostheses might initiate an immune reaction leading to an increased frequency of structural valve deterioration in patients with blood type B or O. The aim was to analyse the association between ABO blood type and porcine bioprosthetic aortic valve degeneration.DesignObservational nationwide cohort study.SettingSwedish population-based study.ParticipantsAdult patients (n=3417) who underwent surgical aortic valve replacement and received porcine bioprosthetic aortic valves between 1995 and 2012 from the Swedish Web system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies register. The study database was enriched with information from other national registers.ExposureThe patients were categorised into type A/AB and type B/O blood groups.Primary and secondary outcome measuresPrimary outcome measure was aortic valve reoperation, and secondary outcomes were heart failure and all-cause mortality. We report risk estimates that account for the competing risk of death.ResultsIn total, 3417 patients were identified: 1724 (50.5%) with blood type A/AB and 1693 (49.5%) with blood type B/O. Both groups had similar baseline characteristics. The cumulative incidence of aortic valve reoperation was 3.4% (95% CI 2.5% to 4.4%) and 3.6% (95% CI 2.6% to 4.6%) in the type B/O and the A/AB group, respectively, at 15 years of follow-up (absolute risk difference: −0.2% (95% CI −1.5% to 1.2%)). There was no significantly increased risk for aortic valve reoperation in patients with blood type B/O compared with type A/AB (HR 0.95, 95% CI 0.62 to 1.45). There was no significant difference in absolute or relative risk of heart failure or death between the groups.ConclusionsWe found no significant association between patient blood type and clinical manifestations of structural valve deterioration following porcine aortic valve replacement. Our findings suggest that it is safe to use porcine bioprosthetic valves without consideration of ABO blood type in the recipient.Trial registration numberNCT02276950

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Food and Fiber Animal Transfusion Medicine

Cited by 3 publications

References 50 publications

Anaemia in South American camelids – an overview of clinical and laboratory diagnostics

Anaemia in South American camelids – an overview of clinical and laboratory diagnostics

Blood, Lymph, and Immune Systems

ABO blood type and risk of porcine bioprosthetic aortic valve degeneration: SWEDEHEART observational cohort study

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