2018
DOI: 10.1590/0074-02760180053
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Follow up of a robust meta-signature to identify Zika virus infection in Aedes aegypti: another brick in the wall

Abstract: The mosquito Aedes aegypti is the main vector of several arthropod-borne diseases that have global impacts. In a previous meta-analysis, our group identified a vector gene set containing 110 genes strongly associated with infections of dengue, West Nile and yellow fever viruses. Of these 110 genes, four genes allowed a highly accurate classification of infected status. More recently, a new study of Ae. aegypti infected with Zika virus (ZIKV) was published, providing new data to investigate whether this “infect… Show more

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Cited by 4 publications
(1 citation statement)
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“…Applicability of other assays such as the Lawrence Livermore Microbial Detection Array (LLMDA) revealed the presence of mosquito-borne viruses and insect-specific viruses in field-collected mosquitoes with similar limitations [24]. Recently, in 2018, Fukutani et al [25,26] proposed an innovative approach, based on the transcriptomic response of the vectors to various arboviruses. In short, they listed a group of co-regulated genes whose expression levels significantly changed in vectors infected by different viruses.…”
Section: Introductionmentioning
confidence: 99%
“…Applicability of other assays such as the Lawrence Livermore Microbial Detection Array (LLMDA) revealed the presence of mosquito-borne viruses and insect-specific viruses in field-collected mosquitoes with similar limitations [24]. Recently, in 2018, Fukutani et al [25,26] proposed an innovative approach, based on the transcriptomic response of the vectors to various arboviruses. In short, they listed a group of co-regulated genes whose expression levels significantly changed in vectors infected by different viruses.…”
Section: Introductionmentioning
confidence: 99%