The impact of ZIKV infection on gene expression in neural cells over time
Moreno Magalhães de Souza Rodrigues,
Antonio Marques Pereira Júnior,
Eduardo Rocha Fukutani
et al.
Abstract:Zika virus (ZIKV) outbreak caused one of the most significant medical emergencies in the Americas due to associated microcephaly in newborns. To evaluate the impact of ZIKV infection on neuronal cells over time, we retrieved gene expression data from several ZIKV-infected samples obtained at different time point post-infection (pi). Differential gene expression analysis was applied at each time point, with more differentially expressed genes (DEG) identified at 72h pi. There were 5 DEGs (PLA2G2F, TMEM71, PKD1L… Show more
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