2011
DOI: 10.5505/jkartaltr.2011.86547
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Follow-up and treatment of a severe tetanus case in the intensive care unit

Abstract: GirişTetanoz, Clostridium tetani tarafından yara yerinden salınan tetanospazmin (ekzotoksin) isimli güçlü bir nörotoksin etkisiyle kontrol edilemeyen kas spazmları ile seyreden bir hastalıktır. Tetanospazmin alfa motor nöronların nöromusküler kavşağından sinir sistemine girer. Toksin buradan retrograt transport ile nö-ronal hücrelerin gövdesine ulaşır. Spinal kord veya beyin sapına gelen toksin, hücre dışı boşluğa ve buradan da presinaptik inhibitör hücrelere geçer. Bu hüc-reler transmitör olarak glisin ve GAB… Show more

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“…Also, primary immunizations of these patients were found to be missing. [7][8][9][10] There is no surveillance for tetanus vaccination in adults in Turkey According to surveillance data collected by the Department of Communicable Diseases, 46 of 62 reported cases of tetanus (74.2%) diagnosed between 2012 and 2016 were 45 years and older. 11 In Turkey, 3-dose vaccination is recommended for primary immunization in adults for tetanus protection by the Standing Committee on Vaccination.…”
Section: Discussionmentioning
confidence: 99%
“…Also, primary immunizations of these patients were found to be missing. [7][8][9][10] There is no surveillance for tetanus vaccination in adults in Turkey According to surveillance data collected by the Department of Communicable Diseases, 46 of 62 reported cases of tetanus (74.2%) diagnosed between 2012 and 2016 were 45 years and older. 11 In Turkey, 3-dose vaccination is recommended for primary immunization in adults for tetanus protection by the Standing Committee on Vaccination.…”
Section: Discussionmentioning
confidence: 99%