Follow-Up After Radical Surgery for Colorectal Cancer. Design of a Randomized Study

Kronborg, O; Fenger, Claus; Deichgräber, E; Hansen, Lise

doi:10.3109/00365528809096975

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1991

2019

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Cited by 27 publications

(2 citation statements)

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“…We identified seven potentially eligible randomised controlled trials,17 – 23 five of which met our inclusion criteria 17 – 21. Two trials reported preliminary results 24 25; two also published on related topics 26 – 28. We also identified six ongoing trials or trials in preparation (box 2).…”

Section: Resultsmentioning

confidence: 99%

Impact on survival of intensive follow up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials

Renehan

Egger

Saunders

et al. 2002

BMJ

603

388

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Section: Resultsmentioning

confidence: 99%

Impact on survival of intensive follow up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials

Renehan

Egger

Saunders

et al. 2002

BMJ

603

388

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“…Also, there is a fairly high rate of new adenoma formation. There are few prospective studies of this, but a Danish study [48] of some 823 patients has shown a new adenoma formation rate of 20% at 2 years and 30% at 4 years. Williams and Macrae [49] reported 114 (37%) of 308 new adenomas at a mean follow-up of 3.6 years.…”

Section: Intermediate End Pointsmentioning

confidence: 99%

Intervention studies in adenoma patients

Armitage

1991

World j. surg.

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The decision to treat patients with recurrent colorectal cancer

Nelson

1993

Cancer

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Although universally performed, postoperative diagnostic screening in patients with colorectal cancer has not been demonstrated to diminish overall mortality. Such screening often leads to second‐look surgery, with many anecdotal successes but again no evidence that overall mortality is reduced. The cost of such interventions is at least $1 billion dollars per year in the United States and may be twice that amount. The research that is needed to support postoperative screening and surgery is feasible and economically easily justified. The endpoints must be shifted from that of previous studies, which have focused on sensitivity of screening techniques, to mortality. Such a study is ongoing in Denmark, and early results of that study should be reported soon.

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Follow-Up After Radical Surgery for Colorectal Cancer. Design of a Randomized Study

Cited by 27 publications

References 8 publications

Impact on survival of intensive follow up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials

Impact on survival of intensive follow up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials

Intervention studies in adenoma patients

The decision to treat patients with recurrent colorectal cancer

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