Follicular mucinosis, mycosis fungoides, and acute myeloid leukemia.

Follicular Mucinosis in a Male Adolescent with a History of Acute Myelogenous Leukemia and Graft‐versus‐Host Disease

“…There are only three reported cases, all in adults, of follicular mucinosis arising in the setting of AML: a 60‐year‐old man who presented with follicular mucinosis and was later found to have AML in the absence of mycosis fungoides ; a 60‐year‐old man with mycosis fungoides–associated follicular mucinosis who subsequently developed AML ; and a 32‐year‐old woman with AML who developed mycosis fungoides–associated follicular mucinosis 100 days after allogeneic BMT . This is the first reported case of follicular mucinosis arising in an adolescent with AML and acute GVHD after an allogeneic BMT.…”

“…Even in the case of cutaneous B‐cell lymphoma associated with follicular mucinosis, involved hair follicles were infiltrated with reactive polyclonal T‐cells rather than monoclonal B‐cells . In patients with leukemia, cell‐mediated immune mechanisms can be significantly altered, potentially leaving them more susceptible to the development of follicular mucinosis or a lymphoproliferative disorder . Hence it is important that these patients be closely monitored for the subtlest of skin changes because they may be a clue to an underlying change in disease status.…”

Concomitant B Hairy Cell Leukemia and Mycosis Fungoides in an Elderly Man

“…A thorough review of the literature on PubMed, using the search terms (“mycosis fungoides” OR “cutaneous T-cell lymphoma”) AND (leukemia OR leukaemia OR lymphoma OR “lymphoid malignancy” OR “Hodgkin's disease” OR “non-Hodgkin's disease” OR “multiple myeloma” OR “B-cell”), identified 68 cases of concomitant mycosis fungoides and a lymphoid malignancy [ 2 , 4 , 5 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 ]. Narrowing the results, we were able to find 5 cases of hairy cell leukemia along with mycosis fungoides reported [ 2 , 5 ].…”