Follicular fluid total antioxidant capacity and ischemia modified albumin levels in polycystic ovary syndrome

Duzguner, Ipek Nur Balin; Taşçı, Yasemin; Çağlar, Gamze Sinem; Dilbaz, Berna; Demırtaş, Selda; Kaplanoğlu, İskender; Duzguner, Soner

doi:10.1016/j.fertnstert.2014.07.944

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Oxidative stress arises due to the generation of ROS in in vitro culture (IVC) conditions, which leads to a reduction in embryonic development because of increased turnover of oocytes, thereby resulting in spontaneous damage to mitochondria and a subsequent reduction in adenosine triphosphate (ATP) synthesis, which in turn causes a decrease in the developmental competence of oocytes (Jagannathan et al 2016;Khazaei and Aghaz 2017;Sasaki et al 2019). The in vivo environment contains oxygen scavengers in the follicular and oviduct fluids to protect oocytes and embryos from oxidative stress (Duzguner et al 2014). This is because the process of oocyte protection plays a critical role against the effects of ROS at the preimplantation embryonic developmental stage.…”

Section: Introductionmentioning

confidence: 99%

Gene Expression and In Vitro Maturation of Sheep Oocytes using Bee Pollen and Bee Honey as Medium Supplements

Kaabi¹

2021

IJAB

View full text Add to dashboard Cite

This study was conducted to investigate the effects of raw honey obtained from black seed or Sider and honeybee pollen as an additive in sheep oocyte maturation medium on the oocyte maturation rate, changes in oocyte glutathione (GSH) levels and expression of developmental candidate genes (GDF-9, MPF, C-MOS, IGF-1, BAX). Healthy immature oocytes of Najdi sheep were cultured in a medium supplemented with 5.0% Sider or Nigella sativa (black seed) honey + 1.0 μg/mL honeybee pollen, and after 24 h of incubation, the effects on the improvement of in vitro oocyte maturation were evaluated. Results demonstrated that the mean oocyte maturation rate was the best in group treated with 5% N. sativa (Group 3) compared with group treated with Sider or N. sativa honey (Group 1A and B, respectively). Mean GSH level was higher in Group 3 oocytes (11.09 ± 0.29 nmol) than in Group 2 oocytes (honey alone; 10.93 ± 0.57; P ≤ 0.05). Mean GSH levels were significantly decreased in Group 1. Expression analysis of candidate genes showed significant upregulation of GDF-9, cyclin B, C-MOS and IGF 1 genes in Group 3 and downregulation of BAX compared with control Group 1. In conclusion, addition of 1.0 μg/mL honeybee pollen along with one of two types of bee honey (Sider and N. sativa) at 5% concentration to the in vitro maturation medium of Najdi sheep oocytes has a beneficial effect in improving the maturation rate and gene expression and increasing the glutathione concentration in matured oocytes. © 2020 Friends Science Publishers

show abstract

Section: Introductionmentioning

confidence: 99%

Gene Expression and In Vitro Maturation of Sheep Oocytes using Bee Pollen and Bee Honey as Medium Supplements

Kaabi¹

2021

IJAB

View full text Add to dashboard Cite

show abstract

Ischemia-Modified Albumin in Gynecology

2021

View full text Add to dashboard Cite

Background: Ischemia-modified albumin (IMA) is an oxidative stress marker used to assess the presence and severity of oxidative stress. This marker was first used for early diagnosis of myocardial ischemia. Materials & methods: A variety of IMA studies were carried out to show the effect of oxidative stress on gynecological disorders. Conclusion: This analysis summarizes the literature by conducting electronic research on the relationship between IMA and gynecological disorders.

show abstract

Follicular fluid total antioxidant capacity and ischemia modified albumin levels in polycystic ovary syndrome

Cited by 2 publications

References 0 publications

Gene Expression and In Vitro Maturation of Sheep Oocytes using Bee Pollen and Bee Honey as Medium Supplements

Gene Expression and In Vitro Maturation of Sheep Oocytes using Bee Pollen and Bee Honey as Medium Supplements

Ischemia-Modified Albumin in Gynecology

Contact Info

Product

Resources

About