Folk uses of some lichens in Sikkim

Saklani, Arvind; Upreti, D. K.

doi:10.1016/0378-8741(92)90038-s

Cited by 36 publications

(20 citation statements)

References 4 publications

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“…Lichen and lichen products have been used for centuries in traditional medicines and still have large importance as alternative treatments in many countries in the world. [7] Numerous researchers have found various biological activities of lichens, which justified the long-term use of some of them in the traditional medicine. Lichen substances are secondary metabolites of lichens, which include dibenzofurans, depsidones, xanthones and terpene derivatives.…”

Section: Introductionmentioning

confidence: 99%

ASSESSMENT OF THE ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF A LICHEN, EVERNIASTRUM CIRRHATUM (FR.) HALE ex. SIPMAN

Mandal¹

2017

WJPPS

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Free radicals generated in system induce oxidative stress related diseases. Recent research is focused on plants and phytocompounds to avoid various side effects. The present study is aimed to evaluate the free radical scavenging potential along with phytochemical screening of the 70% methanolic extract of a lichen, Everniastrum cirrhatum (Fr.) Hale (ECME). ECME was tested for its in vitro total antioxidant capacities and various other reactive oxygen and nitrogen species (ROS, RNS) scavenging potentials. For further insight, phytochemical screening through qualitative and quantitative analyses along with HPLC standardization were performed. It was observed that ECME showed total antioxidant capacity with TEAC value of 0.384 ± 0.0074 as compared to Trolox. The lichen also showed excellent ROS and RNS scavenging capacities as it scavenges hydroxyl, superoxide, hypochlorous acid, nitric oxide and peroxynitrite radicals with IC 50 values of 208. 09 ± 6.36, 142.26 ± 3.17, 150.07 ± 3.01, 118.19 ± 5.99 and 3037.07 ± 222.43 µg/ml respectively. Singlet oxygen is also scavenged but to a lesser extent by ECME. Phytochemical analyses of ECME showed greater presence of alkaloids, phenolics, flavonoids like compounds as compared to other phytocompounds.Moreover HPLC analysis of ECME revealed the presence of antioxidant phytochemicals like purpurin, usnic acid, tannic acid, reserpine and rutin at various retention times. The in vitro results show that ECME possesses promising antioxidant and free radical scavenging

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Section: Introductionmentioning

confidence: 99%

ASSESSMENT OF THE ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF A LICHEN, EVERNIASTRUM CIRRHATUM (FR.) HALE ex. SIPMAN

Mandal¹

2017

WJPPS

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“…In various systems of traditional medicine worldwide, including the Indian system of medicine, these lichen species are said to effectively cure dyspepsia, bleeding piles, bronchitis, scabies, stomach disorders, and many disorders of blood and heart (Saklani & Upreti, 1992;Lal & Upreti, 1995;Negi & Kareem, 1996;Sochting, 1999).…”

Section: Introductionmentioning

confidence: 99%

Antimycobacterial Activity of Lichens

Gupta

Darokar

Saikia

et al. 2007

Pharmaceutical Biology

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Ethanol extracts of nine lichen species, namely Everniastrum cirrhatum (Fr.) Hale ex Sipman (Parmeliaceae), Flavoparmelia caperata (L) Hale (Parmeliaceae), Heterodermia leucomela (L) Poelt (Physciaceae), Lecanora flavidorufa Hue (Lecanoraceae), Leptogium pedicellatum P.M. Jorg (Collemataceae), Lobaria isidiosa (Bory) Trevisan (Stictaceae), Rimelia reticulata (Taylor) Hale and Fletcher (Parmeliaceae), Phaeophyscia hispidula (Ach.) Essl (Physciaceae), and Stereocaulon foliolosum Nyl. (Stereocaulaceae), were evaluated for antimycobacteral properties against Mycobacterium tuberculosis H 37 Rv and H 37 Ra strains using the radiometric BACTEC method. Among the tested lichens, the virulent strain of M. tuberculosis H 37 Rv was found more susceptible to ethanol extract of F. caperata and H. leucomela (MIC 250 mg=mL). E. cirrhatum, R. reticulata, and S. foliolosum were found active at the concentration of 500 mg=mL. L. isidiosa, L. pedicellatum, P. hispidula, and L. flavidorufa did not exhibit activity at the maximum tested concentration of 1000 mg=mL.

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“…Of these, several lichenized fungi of the Himalayan region are said to effectively cure dyspepsia, bleeding piles, bronchitis, scabies, stomach disorders and many disorders of blood and heart [2][3][4]. Flavoparmelia caperata is part of Ayurvedic and Unani medicines under the name 'Chharila' as carminative and aphrodisiac and considered useful in treatment of intestinal worms and burns [5], Everniastrum cirrhatum relieves headache [6,7].…”

Section: Introductionmentioning

confidence: 99%