Folate content and retention in commonly consumed vegetables in the South Pacific

Maharaj, Prayna; Prasad, Surendra; Devi, R. Sarada Jayalakshmi; Gopalan, Romila D.

doi:10.1016/j.foodchem.2015.02.096

Cited by 25 publications

(12 citation statements)

References 16 publications

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“…These results are in agreement with previous studies, which reported folate contents determined by HPLC to be 20-52 % lower when determined by the microbiological assay (Ruggeri et al 1999;Konings 1999). Recently, in a comparative study among Fijian vegetables, including, Moringa oleifera leaves, taro leaves, bele leaves, amaranth leaves, okra and French bean, maximum total folate was observed in M. oleifera leaves (Maharaj et al 2015).…”

Section: Discussionmentioning

confidence: 99%

Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model

et al. 2015

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Moringa oleifera is an affordable and rich source of dietary folate. Quantification of folate by HPLC showed that 5-formyl-5,6,7,8-tetrahydrofolic acid (502.1 μg/100 g DW) and 5,6,7,8-tetrahydrofolic acid (223.9 μg/100 g DW) as the most dominant forms of folate in M. oleifera leaves. The bioavailability of folate and the effects of folate depletion and repletion on biochemical and molecular markers of folate status were investigated in Wistar rats. Folate deficiency was induced by keeping the animals on a folate deficient diet with 1 % succinyl sulfathiazole (w/w). After the depletion period, animals were repleted with different levels of folic acid and M. oleifera leaves as a source of folate. Feeding the animals on a folate deficient diet for 7 weeks caused a significant (3.4-fold) decrease in serum folate content, compared to non-depleted control animals. Relative bioavailability of folate from dehydrated leaves of M. oleifera was 81.9 %. During folate depletion and repletion, no significant changes in liver glycine N-methyl transferase and 5-methyltetrahydrofolatehomocysteine methyltransferase expression were recorded. In RDA calculations, only 50 % of natural folate is assumed to be bioavailable. Therefore, the bioavailability of folate from Moringa is much higher, suggesting that M. oleifera based food can be used as a significant source of folate.

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Section: Discussionmentioning

confidence: 99%

Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model

et al. 2015

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“…*, **, and *** represent the significance levels at p < .05, .01, and .001, respectively. 10-F-FA, 10-Formyl-tetrahydrofolate; 5,10-CH = THF, 5,10-Methenyltetrahydrofolate; 5-F-THF, 5-Formyl-tetrahydrofolate; 5-M-THF, 5-Methyl-tetrahydrofolate; DHF, dihydrofolate; FA, folic acid; THF, Tetrahydrofolate initial folates were lost by wash leaching, 10%-64% of loss by boiling, and 1%-36% of loss by frying (Delchier et al, 2013;Maharaj et al, 2015). Thus, investigation of folate contents in cooked vegetables is necessary for an accurate estimation of folate accessibility to humans.…”

Section: Vegetable-based Preparationsmentioning

confidence: 99%

Identification of the prepared foods promising for dietary folate intake in Beijing, China

Shariful

Mehmood

Zhang

et al. 2020

Food Science & Nutrition

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“…folium -лист), дрожжи и печень [21].Существует положительная корреляция между заболеваемостью дефектами нервной трубки (например, расщелиной позвоночника, анэнцефалией) у новорожденных и нехваткойфолатов в организме матери. По оценкам, более 75% таких врожденных дефектов могут быть предотвращены своевременным приемомфолатов (чаще всего в форме ФК).Для женщин, которые намерены забеременеть, суточная доза должна составлять не менее 600 мкг/день.Причем, данная доза, должна регулярно поступать в организм женщиныв процессе планирования беременности (рекомендовано за 6 месяцев до зачатия) и на протяжении I-го триместра непосредственной беременности [22].…”

Section: аннотацияunclassified

Prospects of pharmacological research of natural folate forms

Saidov¹,

BAGDASAROVA²,

ISAJANOV³

et al. 2018

JBP

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АННОТАЦИЯ Фолаты (витамин В9)-группа органических соединений-водорастворимый витамин группы B. Включает в себя фолиевую кислоту и ее производные (диглутаматы, триглутаматы, полиглутаматы). Фолиевая кислота-одна из (синтетических) форм фолатов (витамина B9), полученная путем его окисления. Она входит в состав многих мультивитаминных лекарственных препаратов, ею широко обогащаются продукты питания, зерновые продукты и др. Однако, последние исследования показывают, что в качестве ресурса витамина B9 эффективнее использовать натуральный фолат, к примеру, в виде фолат-содержащих продуктов питания, которые чаще всего находится в виде 5-метилтетрагидрофолата (L-5-methyltetrahydrofolate). Для профилактики заболеваний, связанных с дефицитом фолатов, можно принимать лекарственныйпрепарат с активным компонентом 5-метилтетрагидрофолата, связанную с молекулой кальция (Ca-L5-methyltetrahydrofolate), в качестве источника данного витамина. В Узбекистане, существуют огромные перспективы для изучения витаминов группы В: многие растения и их плоды являются их комплексными источниками. Ключевые слова: витамин B9, фолиевая кислота, 5-метилтетрагидрифолат, мегалобластная анемия, дефекты нервной трубки.

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Folate content and retention in commonly consumed vegetables in the South Pacific

Cited by 25 publications

References 16 publications

Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model

Relative bioavailability of folate from the traditional food plant Moringa oleifera L. as evaluated in a rat model

Identification of the prepared foods promising for dietary folate intake in Beijing, China

Prospects of pharmacological research of natural folate forms

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