Focal fluorescence of choroidal melanoma.

Abstract

A 65-year-old man presented to the Oncology Service in January 1984. He had previously undergone intracapsular cataract extractions with implantation of an anterior chamber intraocular lens in both eyes. Over the previous several months he had noted blurred vision in the right eye. Examination revealed visual acuity of 20/80 in the right eye and 20/20 in the left. Ophthalmoscopy of the right eye showed a small amelanotic choroidal melanoma in the inferior macula estimated to be 5-5 x 5 mm in basal diameter (Fig. 1). Ultrasonography showed its thickness to be 3 mm. Fluorescein angiography showed early mottled hyperfluorescence over the entire tumour with a distinct localised hyperfluorescent site just nasal to the centre, which was consistent with an area of retinal pigment epithelial attenuation (Fig. 2). Owing to the tumour's small size and proximity to the disc and macula, we decided to observe the tumour for growth before considering treatment.

Small choroidal melanoma and pseudomelanomas: methods of differential diagnostics (literature review). Part 2

“…Поздняя (через 40 мин) флюоресценция начальных меланом также характеризуется слабой степенью проявления и даже отсутствием флюоресценции [15][16][17][18][19][20][21][22][23] (рис. 1).…”

“…Таким образом, ангиографические симптомы МХ выявляются в разных сочетаниях и степени выраженности, поэтому диагностика изучаемой опухоли с использованием только ФАГ, по мнению многих авторов, проблематична [12,13,15,16,18,19].…”

MRI of Blood Volume and Cellular Uptake of Superparamagnetic Iron in an Animal Model of Choroidal Melanoma

“…The introduction of eye-preserving strategies for the treatment of choroidal melanoma, i.e. radio-and thermotherapy, has partially replaced enucleation and histopathology, but noninvasive imaging studies before and after therapy are limited [13][14][15][16]. Most conventional imaging techniques, i.e.…”