Fnac in the Management of Solitary Thyroid Nodule

Raza, Sohail; Raza, Hamad; Saeed, Zahid A.; Ahmed, Mubasher

doi:10.29309/tpmj/2006.13.04.4934

Cited by 7 publications

(2 citation statements)

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“…The complication risk in both these techniques is negligible with seroma or subcutaneous hematoma formation through FNAC in rare cases. [20][21][22] Similar has also been reported in the present research.…”

Section: Discussionsupporting

confidence: 90%

Thyroid Gland Examination for Thyroid Nodule through Free Hand Fine Needle Aspiration Cytology (FNAC) Versus Ultrasound Guided Core Sampling

Mirani¹,

Ali²,

Kumar³

et al. 2022

PJMHS

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Objective: To compare the free hand fine needle aspiration cytology versus ultrasound guided core sampling for thyroid nodule examination in thyroid gland. Study Design: Retrospective study Place and Duration of Study: Department of Surgery Unit-2, Ghulam Muhammad Mahar Medical College Hospital Sukkur from 1st January 2016 to 31st December 2021. Methodology: One hundred patients were divided in two groups. Group A had 50 patients who undergo ultrasonography through Doppler scanning while Group B had equal number of 50 patients which underwent free hand fine needle aspiration cytology. The clinical details were noted and graded as un-satisfactory or lacking follicular cells or else having <6 groups epithelial cells or having sufficient number of follicular cells. Results: The mean age was 31.5±11.8 years and majority of the patients were females 54% in comparison with 46% males. Insufficient cytopathologic cells were noticed in 18% US guided thyroidal nodule examination while similar insufficiency was seen in 44% fine needle aspiration cytology examination. The adequate cytopathological cells were noticed in 82% Ultrasounds while same was only seen in 56% fine needle aspiration cytology. Conclusion: Ultrasound guided core sampling has presented higher adequate cytology cases in comparison to free hand fine needle aspiration cytology cases. Key words: Fine needle aspiration cytology, Ultrasonography, Thyroid nodule

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Section: Discussionsupporting

confidence: 90%

Thyroid Gland Examination for Thyroid Nodule through Free Hand Fine Needle Aspiration Cytology (FNAC) Versus Ultrasound Guided Core Sampling

Mirani¹,

Ali²,

Kumar³

et al. 2022

PJMHS

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“…Thus it is very important to distinguish these two diseases when planning treatment. The introduction of FNAB 40 years ago substantially improved the preoperative assessment of thyroid lesions due to its high positive and negative predictive value (Raza, Raza, Saeed, & Ahmed, 2006;Handa, Garg, Mohan, & Nagarkar, 2008). In one study, the most consistent cytomorphological features observed in fine needle aspiration smears of Hashimoto's thyroiditis were increased background lymphocytes, lymphocytic infiltration of thyroid follicular cell clusters, and Hurthle cells.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Clinical and Laboratory Limits between Hashitoxicosis and Graves’ Disease

Reis¹,

Feibelmann²,

Ferreira³

et al. 2022

GJHS

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BACKGROUND: Determine the clinical and laboratory features of Hashitoxicosis (Htx) and set standards that will help perform a differential diagnosis with Graves’Disease (GD). SUBJECTS & METHODS: we evaluated 45 patients with Htx (Hashi-group) diagnosed between January/1995 and July/2019 with autoimmune hyperthyroidism and cytology compatible with Hashimoto’s Thyroiditis (HT). The control group consisted of 51 patients with GD (Graves-group). RESULTS: clinical hyperthyroidism, free T4 (FT4), thyroid volume and need for antithyroid drugs were higher in the Graves-Group. Values of anti-thyroid antibodies and TSH were higher in the Hashi-Group. The definitive diagnostic criterion was cytology. Regarding the clinical course, 95% of the Hashi-Group had hyperthyroidism of short duration, while 84.3% of Graves-Group required radioactive iodine (RAI). CONCLUSION: hyperthyroidism due to HT was milder than that associated with GD. In most citology was able to distinguish HT from GD and predict spontaneous resolution preventing unnecessary RAI.

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Cytomorphological Spectrum of Thyroiditis: A Review of 110 Cases

Chandanwale

Nair

Gambhir

et al. 2018

Journal of Thyroid Research

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Introduction Different types of thyroiditis may share some parallel clinical and biochemical features. Timely intervention can significantly reduce morbidity and mortality. Aim Aim of this study is to find the frequency of various thyroiditis, study the cytomorphological features and correlate with clinical findings including radiological findings, thyroid function test, and anti-thyroid peroxidase antibodies (Anti-TPO antibodies). Materials and Methods The study included consecutive 110 cases of thyroiditis. Detailed cytomorphological features were studied and correlated with ultrasonography findings, thyroid function test, anti-thyroid peroxidase antibodies (anti-TPO) and histopathological features where thyroidectomy specimens were received for histopathological examination. Results The majority were Hashimoto's thyroiditis (n = 100) and females (n = 103). Other forms of thyroiditis were Hashimoto's thyroiditis with colloid goiter (n = 5), De Quervain's thyroiditis (n = 3), and one case each of postpartum thyroiditis and Hashimoto's thyroiditis with associated malignancy. The majority of patients were in the age group of 21–40 (n = 70) and the majority (n = 73) had diffuse enlargement of thyroid. The majority of patients were hypothyroid (n = 52). The serum anti-TPO antibodies were elevated in 47 patients out of 71 patients. In the 48 patients who underwent ultrasonography, 38 were diagnosed as having thyroiditis. The most consistent cytomorphological features seen in fine-needle aspiration smears of Hashimoto's thyroiditis were increased background lymphocytes, lymphocytic infiltration of thyroid follicular cell clusters, and Hurthle cells. Conclusion The diagnostic cytological features in Hashimoto's thyroiditis are increased background lymphocytes, lymphocytic infiltration of thyroid follicular cell clusters, and Hurthle cells. FNAC remains the “Gold Standard” for diagnosing Hashimoto's thyroiditis. Clinical history, thyroid function, and biochemical parameters are the key for diagnosis of other forms of thyroiditis.

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Fnac in the Management of Solitary Thyroid Nodule

Cited by 7 publications

References 0 publications

Thyroid Gland Examination for Thyroid Nodule through Free Hand Fine Needle Aspiration Cytology (FNAC) Versus Ultrasound Guided Core Sampling

Thyroid Gland Examination for Thyroid Nodule through Free Hand Fine Needle Aspiration Cytology (FNAC) Versus Ultrasound Guided Core Sampling

Assessment of Clinical and Laboratory Limits between Hashitoxicosis and Graves’ Disease

Cytomorphological Spectrum of Thyroiditis: A Review of 110 Cases

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