fMRI-Determined Language Lateralization in Patients with Unilateral or Mixed Language Dominance According to the Wada Test

Rutten, Geert-Jan; Ramsey, Nick F.; Rijen, Peter C. van; Alpherts, W.C.J.; Veelen, C.W.M. van

doi:10.1006/nimg.2002.1196

Cited by 223 publications

(130 citation statements)

References 49 publications

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“…52,81 When a patient undergoes imaging twice with the same protocol using the same imaging unit, the activation maps will not be exactly the same. 83 Some of the factors that contribute to this variability are known, such as fieldstrength or imaging unit type and artifacts due to movements (for example, respiration and cardiovascular pulsation); these factors can to some extent be controlled in data analysis.…”

Section: Functional Mr Imaging: a Short Introduction To Its Principlementioning

confidence: 99%

“…For clinical use of fMR imaging, there are some strategies to increase the reliability and detection power of brain activation maps. 26,81,83 Absence of activation is another important issue to consider. Failure to detect activity can be caused by several factors, some of which are difficult or impossible to control.…”

Section: Functional Mr Imaging: a Short Introduction To Its Principlementioning

confidence: 99%

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The role of functional magnetic resonance imaging in brain surgery

Rutten

Ramsey

2010

FOC

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New functional neuroimaging techniques are changing our understanding of the human brain, and there is now convincing evidence to move away from the classic and clinical static concepts of functional topography. In a modern neurocognitive view, functions are thought to be represented in dynamic large-scale networks. The authors review the current (limited) role of functional MR imaging in brain surgery and the possibilities of new functional MR imaging techniques for research and neurosurgical practice. A critique of current clinical gold standard techniques (electrocortical stimulation and the Wada test) is given.

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Section: Functional Mr Imaging: a Short Introduction To Its Principlementioning

confidence: 99%

Section: Functional Mr Imaging: a Short Introduction To Its Principlementioning

confidence: 99%

The role of functional magnetic resonance imaging in brain surgery

Rutten

Ramsey

2010

FOC

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“…DLT is correlated to fMRI, with a simultaneous increase in the values resulting from both examinations. A number of other studies have already compared DLT with SAT [17][18][19][20][21] , and fMRI with SAT 9,11,13,15,16,22 , showing a positive relationship and confirming the efficiency of the two tests. The relationship between DLT and fMRI, however has been scarcely studied.…”

Section: Language Hemisphere Dominance: Dlt and Fmrimentioning

confidence: 71%

“…The number of activated voxels in each ROI (L and R) was then counted, and a lateralization index (LI) was calculated as follows [9][10][11][12][13][14][15][16] . The number of activated voxels on the right side is subtracted from the number of activated voxels on the left side, and the result is divided by the sum of the two quantities, LI=(L-R)(L+R).…”

Section: Methodsmentioning

confidence: 99%

Language brain dominance in patients with refractory temporal lobe epilepsy: a comparative study between functional magnetic resonance imaging and dichotic listening test

Fontoura

Branco

Anés

et al. 2008

Arq. Neuro-Psiquiatr.

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-Purpose: To identify brain dominance for language functions with DLT and correlate these results with those obtained from fMRI in patients suffering from intractable temporal lobe epilepsy. Method: This study reports on 13 patients who underwent pre-surgical epileptic evaluation between April and October 2004 at the Epilepsy Surgery Program, Hospital Sao Lucas, PUCRS. In DLT, dominance was assessed through a consonant-vowel task, whereas in fMRI patients performed a verb generation task. Results: Our results identified a correlation between the fMRI lateralization index and the DLT ear predominance index and reply difference index (r=0.6, p=0.02; Pearson Correlation Coefficient), showing positive correlation between results obtained from fMRI and DLT. Conclusion: DLT was found to significantly correlate with fMRI. These findings indicate that DLT (a non-invasive procedure) could be a useful tool to evaluate language brain dominance in pre-surgical epileptic patients as it is cheaper to perform than fMRI.KEy wORDS: dichotic listening test, functional magnetic resonance imaging, refractory temporal lobe epilepsy, brain dominance, language.Determinação de dominância cerebral para linguagem em pacientes com epilepsia refratária de lobo temporal: estudo comparativo entre ressonância magnética funcional e teste de escuta dic�tica teste de escuta dic�tica Resumo -Objetivo: Identificar a dominância cerebral para funções de linguagem através do teste de escuta dicótica (TED) e correlacionar com os resultados de ressonância magnética funcional (RMf) em pacientes com epilepsia refratária de lobo temporal. Método: Foram estudados 13 pacientes com epilepsia refratária de lobo temporal, que realizaram avaliações pré-cirúrgicas no período de abril a outubro de 2004 no Programa de Cirurgia de Epilepsia do Hospital São Lucas da PUCRS. Realizada investigação da dominância hemisférica para linguagem através do TED Consoante-Vogal e da RMf pela geração de verbos. Resultados: Verificou-se a existência de correlação entre os índices de lateralidade (RMf) e os índices de predomínio de orelha e de diferença de resposta (TED) (r=0,6, p=0,02). Conclusão: Existe correlação entre os resultados obtidos através da RMf (índice de lateralidade) e do TED (índice de predomínio de orelha e índice de diferença de resposta) em pacientes com epilepsia refratária de lobo temporal.PALAVRAS-CHAVE: teste de escuta dicótica, ressonância magnética funcional, epilepsia temporal refratária, dominância cerebral, linguagem.

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“…Activation on fMR images and disruption of function as assessed with electrocortical stimulation was within 5 mm in frontal regions and 10 mm in temporal areas. 98,110 Differences in the results of fMR imaging and electrocortical stimulation may be due in part to inability of electrocortical stimulation to map areas deep within sulci, coregistration error in fMR, BOLD identification of draining veins rather than capillaries, or the threshold used for processing fMR images.…”

Section: Functional Mr Imagingmentioning

confidence: 99%

Advances in neuroimaging in patients with epilepsy

Widjaja¹,

Raybaud²

2008

FOC

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Intractable seizures can have a devastating effect on the development of a child. In children with intractable epilepsy that is refractory to medication, surgical treatment may be needed. Magnetic resonance imaging is an essential neuroimaging tool to assist in the identification of an epileptogenic substrate. The interpretation of MR images should be done in the context of clinical knowledge of the seizure symptomatology and electroencephalographic findings. Quantitative processing of structural MR data and advanced MR imaging such as diffusion tensor imaging and MR spectroscopy have the potential to identify subtle lesions that may otherwise have been missed. In addition to lesion localization, identification of eloquent cortex and white matter tracts are also an essential component of epilepsy surgery workup. Functional MR imaging maps the sensorimotor cortex and also lateralizes language. Diffusion tensor imaging tractography can be used to map the corticospinal tracts and the optic radiations. In addition to MR imaging, magnetoencephalography and nuclear medicine studies such as PET and SPECT scanning may be used to lateralize seizure focus when clinical, electrophysiological, and structural MR imaging findings are discordant.

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fMRI-Determined Language Lateralization in Patients with Unilateral or Mixed Language Dominance According to the Wada Test

Cited by 223 publications

References 49 publications

The role of functional magnetic resonance imaging in brain surgery

The role of functional magnetic resonance imaging in brain surgery

Language brain dominance in patients with refractory temporal lobe epilepsy: a comparative study between functional magnetic resonance imaging and dichotic listening test

Advances in neuroimaging in patients with epilepsy

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