Fluorophotometry in Myopic Phakic Eyes With Anterior Chamber Intraocular Lenses to Correct Severe Myopia

The iris-claw intraocular lens (IOL) was recently approved by the U.S. Food and Drug Administration for the correction of refractive disorders. Previous reports are not uniform regarding its potential to induce inflammatory reaction. We report the case of a young healthy patient who experienced persistent and intolerable iritis after implantation of an iris-claw IOL. The iritis was resolved only after explantation of the IOL.

Section: Discussionmentioning

confidence: 99%

Recurrent iritis after implantation of an iris-fixated phakic intraocular lens for the correction of myopia

Kleinmann¹,

Apple²,

Mackool³

2006

“…153 The chronic subclinical inflammation induced by changes in the permeability of the BAB barrier after pIOL implantation also raises the concern of cataract formation, just as in uveitis and diabetes. 8,40,53,56,80 The continuous disruption of the BAB was related to contact between the uveal tissue (iris and ciliary body) and the pIOL. 7 Laser flare-cell meter measurement is an objective and reproducible method for in vivo evaluation of anterior segment inflammation.…”

Section: Intraocular Lens-dependent Factorsmentioning

confidence: 99%

Metaanalysis of cataract development after phakic intraocular lens surgery

Chen

Chang

Kuo

et al. 2008

129

We performed a systematic literature review to determine the incidence of and predisposing factors for cataract after phakic intraocular lens (pIOL) implantation. Of the 6338 eyes reported, 4.35% were noted to have new-onset or preexisting progressive cataract. The incidence of cataract formation was 1.29%, 1.11%, and 9.60% with anterior chamber, iris-fixated, and posterior chamber (PC) pIOLs, respectively. In the PC pIOL group, early cataract formation was related to surgical trauma and late-onset cataract was related to IOL-crystalline lens contact. Analysis of cataract progression in eyes with preexisting cataract showed a progression rate of 29.5% after pIOL surgery. These results suggest that cataract formation is most likely to occur after PC pIOL implantation. Patients with preexisting progressive cataract should be informed about the possibility of cataract progression and possible need for cataract surgery after pIOL implantation. Cataract surgical intervention resulted in restoration of visual acuity.

“…8 In the late 1980s, Worst and Fechner introduced refractive iris-supported IOLs. [9][10][11][12][13][14] Surgeons became hesitant to use these IOLs because the surgical techniques were difficult and invasive and the complications were severe, [15][16][17][18][19] especially those related to endothelial cell damage in eyes with biconcave model IOLs, determining corneal decompensation and bullous keratopathy.…”

mentioning

confidence: 99%

Long-term endothelial changes in phakic eyes after Artisan intraocular lens implantation to correct myopia

Benedetti¹,

Casamenti²,

Benedetti³

2007