1965
DOI: 10.1038/208796a0
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Fluorochrome Stains for Histological Diagnosis of Visceral Mycoses

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Cited by 7 publications
(2 citation statements)
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“…It can bind to DNA [13, 14], RNA [15, 16], lysosome [17, 18], and glycosaminoglycans [19]in living cells as well as in parasites (malaria) [22, 23], fungi [24], bacteria [25], and viruses [26, 27]. It has the capability to emit fluorescence by excitation with light [28, 29, 30].…”
Section: Discussionmentioning
confidence: 99%
“…It can bind to DNA [13, 14], RNA [15, 16], lysosome [17, 18], and glycosaminoglycans [19]in living cells as well as in parasites (malaria) [22, 23], fungi [24], bacteria [25], and viruses [26, 27]. It has the capability to emit fluorescence by excitation with light [28, 29, 30].…”
Section: Discussionmentioning
confidence: 99%
“…AO emits green (533 nm) or orange (656 nm) fluorescence following blue light (492 nm) excitation. Since AO has a very low molecular weight (MW 265), it has the capability to rapidly flow into the cytoplasm through the plasma membrane binding to the DNA, RNA 97 , 98 ) and acidic lysosomes 99 , 100 . AO selectively accumulates in cancer cells, especially in acidic lysosomes, emits fluorescence after blue excitation, and kills cancer cells via apoptosis by activated oxygen.…”
Section: Photodynamic Molecules and Cancermentioning
confidence: 99%