Fluoride toothpastes containing micrometric or nano-sized sodium trimetaphosphate reduce enamel erosion <i>in vitro</i>

Danelon, Marcelle; Pessan, Juliano Pelim; Santos, Vinícius Rodrigues dos; Chiba, Erika Kiyoko; Garcia, L; Camargo, Emerson R.; Delbem, Alberto Carlos Botazzo

doi:10.1080/00016357.2017.1388442

Cited by 14 publications

(12 citation statements)

References 38 publications

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“…Trimetaphosphate also helps reduce the acid diffusion into the enamel (21, 22, 35) even when it is due to breakdown of hydrogen peroxide (Fig. 1).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of new compositions of 10% hydrogen peroxide‐based bleaching agents containing trimetaphosphate and fluoride on enamel demineralization

Santos

Delbem

Danelon

et al. 2020

European J Oral Sciences

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This study evaluated the effect on enamel demineralization of 10% hydrogen peroxide (H2O2) gels containing different concentrations of sodium trimetaphosphate (TMP) and sodium fluoride (NaF) combined with the daily use of fluoridated or placebo dentifrice. Bovine enamel blocks were selected by surface hardness (n = 72) and randomly assigned to one of the following experimental treatments: 10% H2O2; 10% H2O2 + 3% TMP + 0.1% NaF; and 10% H2O2 + 0.3% TMP + 0.05% NaF, each with or without fluoridated dentifrice. H2O2‐based gels were applied for 30 min d−1 followed by treatment with dentifrice (1 min). Enamels blocks were stored in artificial saliva at 37°C between sessions during the 14 days of experiment. Percentage of surface hardness loss (%SH) was calculated, and the blocks were cut into halves to analyze cross‐sectional hardness (ΔKHN). Polarized light microscopy images were obtained of the longitudinal sections of the samples. Enamel treated with fluoridated dentifrice presented lower hardness loss than those treated with placebo dentifrice (%SH and ΔKHN). Use of TMP‐ and NaF‐based gels, regardless of concentration, led to the lowest %SH values. Specimens treated with 10% H2O2 gel had the highest %SH and ΔKHN values. Gels with 10% H2O2 + 3% TMP + 0.1% NaF showed the lowest ΔKHN values. Microscopy images clearly showed that the addition of TMP and NaF to the H2O2‐based gels was effective in reducing the loss of hardness, and the fluoridated dentifrice helped minimize it in all treatments.

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“…Trimetaphosphate also helps reduce the acid diffusion into the enamel (21, 22, 35) even when it is due to breakdown of hydrogen peroxide (Fig. 1).…”

Section: Discussionmentioning

confidence: 99%

Evaluation of new compositions of 10% hydrogen peroxide‐based bleaching agents containing trimetaphosphate and fluoride on enamel demineralization

Santos

Delbem

Danelon

et al. 2020

European J Oral Sciences

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“…Die Datenlage zur Effektivität von Polyphosphaten zur Wirksamkeitssteigerung von zinnhaltigen Mundhygieneprodukten ist jedoch nicht ganz eindeutig und scheint von der Art des Polyphosphats abzuhängen [34]. Während verschiedene Studien eine Verbesserung der antierosiven Wirkung durch deren Zusatz zu zinnhaltigen Mundhygieneprodukten belegen konnten [35,36], zeigten andere Studien keine Effektsteigerung durch diese Verbindungen [37 -39]. Auch Pyrophosphate (Diphosphate) wurden untersucht, zeigten jedoch nicht den gewünschten wirksamkeitssteigernden Effekt [40].…”

Section: Fluoride Und Polyvalente Metallionenunclassified

Moderne Präventions- und Therapiekonzepte bei dentalen Erosionen – Bewertung therapeutischer Wirkstoffe

Schlüter¹,

Müller²,

Luka³

2021

Zahnmedizin up2date

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“…This erosive cycle simulated the erosion process in the oral cavity, intercalating citric acid demineralization (1% citric acid; 3.5 pH) 16 and treatment with toothpaste slurry. 17 Half the surface area of the specimens were protected with a layer of acid-resistant varnish (Risqué Colorless) for reference to allow the analysis of surface profilometry after the erosive cycle. The erosion cycling model was of 5 days.…”

Section: Erosive Challengementioning

confidence: 99%

“…The erosion cycling model was of 5 days. 17 Before the 1 st erosive challenge of each day, the specimens were immersed individually for 1 h in human saliva at 37ºC under agitation (100 rpm) and subsequently in the respective erosive solutions for 1 min, 4 times daily, 17 with 1 h of interval. Citric acid was handled daily and renewed at each erosion episode.…”

Section: Erosive Challengementioning

confidence: 99%

Influence of cigarette smoke combined with different toothpastes on enamel erosion

Ferraz

Pini²,

Ambrosano

et al. 2019

Braz. oral res.

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This in vitro study aimed to evaluate the effect of different toothpastes on dental enamel subjected to an erosive cycle with and without exposure to cigarette smoke. Bovine enamel specimens were randomly allocated into 12 groups (n = 12). For the in vitro simulation of smoking, half the groups underwent an exposure cycle of 20 cigarettes per day for 5 days. Subsequently, all groups were subjected to a 5-day erosion cycle intercalating demineralization (1 min; 1% citric acid; pH = 3.5) and treatment with toothpaste slurries (2 min) of NaF, SnF 2 , F/Sn/Chitosan, F/CaSiO 3 /Na 3 PO 4 , and F/bioactive glass. The control group was immersed in distilled water. Surface microhardness (SMH) was measured initially, after exposure to smoke, and after the erosive cycle, and %SMH was calculated. At the end of the experimental cycle, surface roughness, profilometry, and atomic force microscopy (AFM) were performed. SMH increased after exposure to cigarette smoke (p < 0.05). After the erosive cycle, there were no differences between the presence and absence of cigarette smoke exposure in SMH and roughness (p > 0.05). Besides increasing enamel SMH, cigarette smoke did not prevent enamel loss after the erosion cycle (p < 0.05). In profilometry, roughness and surface loss had the lowest values in the groups treated with SnF 2 and F/Sn/Chitosan (p < 0.05). AFM showed lower mineral loss with F/CaSiO 3 /Na 3 PO 4 and F/Sn/Chitosan. For all groups, except F/CaSiO 3 /Na 3 PO 4 , cigarette smoke resulted in higher enamel wear. F/Sn/Chitosan showed the best results against erosion.

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Fluoride toothpastes containing micrometric or nano-sized sodium trimetaphosphate reduce enamel erosion in vitro

Abstract: The addition of 3% TMPnano to 1100 ppm F toothpastes significantly increases the protective effect against enamel erosion in vitro when compared with its counterparts with micrometric TMP or without TMP. This effect was not influenced by the presence of acquired enamel pellicle and saliva.

Cited by 14 publications

References 38 publications

Evaluation of new compositions of 10% hydrogen peroxide‐based bleaching agents containing trimetaphosphate and fluoride on enamel demineralization

Evaluation of new compositions of 10% hydrogen peroxide‐based bleaching agents containing trimetaphosphate and fluoride on enamel demineralization

Moderne Präventions- und Therapiekonzepte bei dentalen Erosionen – Bewertung therapeutischer Wirkstoffe

Influence of cigarette smoke combined with different toothpastes on enamel erosion

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