Fluoride released from glass-ionomer cement is responsible to inhibit the acid production of caries-related oral streptococci

Nakajo, Kazuko; Imazato, Satoshi; Takahashi, Yusuke; Kiba, Wakako; Ebisu, Shigeyuki; Takahashi, Nobuhiro

doi:10.1016/j.dental.2008.10.014

Cited by 97 publications

(77 citation statements)

References 40 publications

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“…Amongst the dental restorative materials used in dentistry, the conventional glass ionomer cement (GIC) has been found to have antibacterial effects. It was reported that the population of Streptococcus mutans (S. mutans) on the surface of GIC fillings was lower than on composite resin fillings 4,5) . The fluoride released from GICs could prevent caries progression by favoring remineralization or by interfering with the growth or metabolism of remaining cariogenic bacteria [6][7][8] .…”

Section: Introductionmentioning

confidence: 99%

Antibacterial activity of composite resin with glass-ionomer filler particles

et al. 2010

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The purpose of this study was to examine the antibacterial activity of composite resin with glass-ionomer filler particles versus that of contemporary commercial composite resins. Three composite resins were used: Beautifil II (containing S-PRG filler), Clearfil AP-X, and Filtek Z250. Resin blocks were bonded to maxillary first molars, and plaque accumulation on the resin block surface was examined after 8 hours. For the antibacterial test, the number of Streptococcus mutans in contact with the composite resin blocks after incubation for 12 hours was determined, and adherence of radiolabeled bacteria was evaluated. Less dental plaque was formed on Beautifil II resin block as compared to the other two materials. Antibacterial test revealed that there were no significant differences in the number of Streptococcus mutans among the three composite resins. However, the adherence of radiolabeled bacteria to the saliva-treated resin surface was significantly (p<0.01) lower in Beautifil II than in the other two materials. These results suggested that Beautifil II could reduce dental plaque formation and bacterial adherence, leading to prevention of secondary caries.

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Section: Introductionmentioning

confidence: 99%

Antibacterial activity of composite resin with glass-ionomer filler particles

et al. 2010

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“…[8] In another study conducted in Japan by Nakajo et al, indicate that GIC fillings in the oral cavity, reduce bacterial acid production, and the subsequent bacterial growth may decrease, creating the cario-static environment. [9] In a study conducted by Chau et al, results suggest that the anti-cariogenic biofilm activity of GICs is closely correlated with their fluoride release rate during biofilm formation. [10,11] The antimicrobial activity of the GICs could be related to the synergistic action of acid and fluoride release of the cement …”

Section: Discussionmentioning

confidence: 99%

Effect of Acid and Fluoride Release from Four Glass Ionomer Cements on Streptococcus mutans: An In Vitro Study

Mahuli¹,

Mahuli²,

Ramanarayanan³

et al. 2015

IJDHC

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Objectives:The objective was to evaluate fluoride and acid release from four glass ionomer cements (GICs) over time and to evaluate and compare their effect on Streptococcus mutans over time. Materials and Methods: The fluoride and acid release from the prepared samples (GICs, Miracle Mix, Fuji IX, d-tech ® , Ketac Molar) were measured daily using digital fluoride meter and pH meter, respectively, after placing them in deionized distilled water for 15 days. The water was replaced daily. The samples were aged by placing them in distilled water for 1, 3, 5, and 7 days. The antimicrobial activity was assessed by measuring the zone of inhibition around the samples (fresh and aged) placed on the bacterial cultures after 48 h of incubation. Mean and standard deviation were calculated. Pearson's correlation coefficient was used. P < 0.05 was considered statistically significant. Results: The antimicrobial activity of the four GICs was greatest immediately after the cements were mixed. The greatest fluoride and acid release was from d-tech. Conclusion: Both acid and fluoride release that contributed to the antibacterial activity of the Glass ionomer cements reduced significantly as the cement aged.

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“…Some dental restorations release metallic or fluoride ions into the environment with a possible influence on the vitality of the adherent bacteria 12) . Glass ionomer cements (GICs), which are widely used as a restorative material, contain a high percentage of F. It was reported that the population of S. mutans on the surface of GIC fillings is lower than that on composite resin fillings 18) . Also, the release of fluoride from GICs can prevent caries progression by interfering with the growth or metabolism of the remaining cariogenic bacteria 19,20) .…”

Section: Discussionmentioning

confidence: 99%

“…It has already been discussed that other components simultaneously released from ionomeric-based (e.g., aluminum) may be involved in the antibacterial activity of the materials 26,27) . Moreover, Nakajo et al reported that ions of silica, aluminum and fluoride released from glass ionomer cements inhibited the fall in pH and acid production as well as streptococci growth 18) . Thus, the capacity of restorative materials to release such agents as well as the ability of their incorporation in the adjacent dental structure should be considered in the case of tooth protection against secondary caries.…”

Section: Discussionmentioning

confidence: 99%

Adherence of Streptococcus sanguinis and Streptococcus mutans to salivacoated S-PRG resin blocks

et al. 2014

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This in vitro study performed elemental analysis of the ions absorbed into the salivary coat covering the surfaces of S-PRG resin blocks and assessed the adherence of Streptococcus sanguinis and Streptococcus mutans to these saliva-coated S-PRG resin blocks. Elemental analysis of ions absorbed into the salivary coat of resin blocks exposed to the saliva was performed using an inductive coupled plasma atomic emission spectrometer and the fluoride electrode method. Quantitative adherence of radio-labeled test bacteria to the resin blocks was determined. As the results, the saliva-coated S-PRG resin showed significantly greater amounts of absorbed B, Al, Si, Sr, and F than the saliva-coated unfilled resin. It was of particular significance that the salivary coating of the S-PRG resin reduced the adherence of S. mutans to this resin. However, in the case of S. sanguinis, no significant difference in adherence could be recognized between saliva-coated S-PRG resin and saliva-coated unfilled resin.

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Fluoride released from glass-ionomer cement is responsible to inhibit the acid production of caries-related oral streptococci

Cited by 97 publications

References 40 publications

Antibacterial activity of composite resin with glass-ionomer filler particles

Antibacterial activity of composite resin with glass-ionomer filler particles

Effect of Acid and Fluoride Release from Four Glass Ionomer Cements on Streptococcus mutans: An In Vitro Study

Adherence of Streptococcus sanguinis and Streptococcus mutans to salivacoated S-PRG resin blocks

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