Fluorescent Mannose-Functionalized Hyperbranched Poly(amido amine)s: Synthesis and Interaction with E. coli

Yang, Wen; Pan, Cai‐Yuan; Ming-deng, Luo; Zhang, Hongbin

doi:10.1021/bm100307d

Cited by 99 publications

(86 citation statements)

References 36 publications

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“…3. Multicolor emission behaviors have been previously observed in various polymeric systems including polypyrene nanofibres [36], polyvinyl pyridine gels [37], polyamidoamine nanoparticles [38], hyper branched polyamidoamines [39], nitro-substituted pyrene oligomers [40] and oligo (4-hydroxyquinoline) [41]. In general, this unusual property is explained by the broad chain dispersity of resulting product.…”

Section: Resultsmentioning

confidence: 84%

Chemical oxidative polymerization, optical, electrochemical and kinetic studies of 8-amino-2-naphthol

et al. 2015

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Here the polymerization of 8-amino-2-naphthol (AN) is reported without use of an additional external template, surfactants or functional dopants. For this, NaOCl and hydrochloride acid solution (1.0 M) were used as oxidant and reaction medium, respectively. The structure of oligomer was elucidated by FT-IR, UV-vis and 1 H-NMR techniques. The number average molecular weight of oligomer was found to be 2200Da with a polydispersity index of 1.4 by size exclusion chromatography. This oligomer exhibited a multicolor emission behavior as it was excited at different wavelenghts. Redox states were clarified by cyclic voltammetry (CV) technique and the relationship between anodic/cathodic peak currents vs. scan rates was determined. Thermal analysis and XRD data assigned that the resulting oligomer was in a semi-crystalline form. The activation energy related to the solid state decomposition was calculated from differential and integral non-isothermal methods and the lowest value using Kissinger procedures was determined to be 79.53 kJ/mol in N 2 atmosphere.

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Section: Resultsmentioning

confidence: 84%

Chemical oxidative polymerization, optical, electrochemical and kinetic studies of 8-amino-2-naphthol

et al. 2015

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“…28 In this study, two amino monomers, CHL and CAR, were used to introduce guanidino groups into SS-PAAs, leading to the synthesis of CAR-CBA and CHL-CBA following the route shown in Figure 1. CHL is well known and widely used as a bacteriostatic agent in the pharmaceutical field or as a finishing agent in the textile industry with good bioactivity, biocompatibility, and low cytotoxicity.…”

Section: Results and Discussion Synthesis Of Car-cba And Chl-cbamentioning

confidence: 99%

Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery

Zhang

Xing

et al. 2016

IJN

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Guanidinylated poly(amido amine)s with multiple disulfide linkages (Gua-SS-PAAs) were designed and constructed as nonviral gene carriers. The main chains of these novel carriers were synthesized based on monomers containing guanidino groups (guanidine hydrochloride and chlorhexidine), which could avoid complicated side-chain-modification reactions while introducing the guanidino groups. The synthesized Gua-SS-PAAs polymers were characterized by 1 H nuclear magnetic resonance, molecular weight, and polydispersity. Furthermore, Gua-SS-PAAs polymers were complexed with p DNA, and the properties of the complexes were determined, including entrapment efficiency, particle size, ζ -potential, atomic force microscopy images, stability, DNA complexation ability, reduction sensitivity, cytotoxicity, and transfection efficiency. The new Gua-SS-PAAs carriers exhibited higher transfection efficiency and lower cytotoxicity compared with two widely used gene delivery carriers, polyethylenimine and lipofectamine 2000. Furthermore, the relationship between the side-chain structure and morphological/biological properties was extrapolated, and the results showed that guanidine in the side chain aids in the improvement of transfection efficiency. In addition, the introduction of guanidino group might confer the new carriers with nuclear localization function compared to carriers without it.

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“…These PPE particles could have potential in applications such as affinity chromatography to Bcatchĝ lycan binding proteins. An interesting type of mannosylated polymer 28 consisting of amidoamine building blocks was also shown to be useful in bacterial detection [108]. These unique polymers do not possess conventional fluorophores, yet display fluorescence that is dependent on the size of the polymer.…”

Section: Glycan Decorated Fluorescent Polymersmentioning

confidence: 99%

Fluorescently labelled glycans and their applications

Yan

Yalagala

Yan³

2015

Glycoconj J

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This review summarises the literature on the synthesis and applications of fluorescently labelled carbohydrates. Due to the sensitivity of fluorescent detection, this approach provides a useful tool to study processes involving glycans. A few general categories of labelling are presented, in situ labelling of carbohydrates with fluorophores, fluorescently labelled glycolipids, fluorogenic glycans, pre-formed fluorescent glycans for intracellular applications, glycan-decorated fluorescent polymers, fluorescent glyconanoparticles, and other functional fluorescent glycans.

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Fluorescent Mannose-Functionalized Hyperbranched Poly(amido amine)s: Synthesis and Interaction with E. coli

Cited by 99 publications

References 36 publications

Chemical oxidative polymerization, optical, electrochemical and kinetic studies of 8-amino-2-naphthol

Chemical oxidative polymerization, optical, electrochemical and kinetic studies of 8-amino-2-naphthol

Guanidinylated bioresponsive poly(amido amine)s designed for intranuclear gene delivery

Fluorescently labelled glycans and their applications

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