Fluorescence diagnosis of non-muscle-invasive bladder cancer: problems and achievements

Trushin, Anton; Головащенко, М. П.; Филоненко, Е. В.

doi:10.17116/onkolog2018706174

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Необходимость раннего распознавании микроскопических опухолей, часто внешне не отличающихся от окружающих здоровых тканей, стала толчком к изучения методов световой визуализации злокачественных новообразований. На сегодняшний день для этих целей широко применяется флюоресцентная диагностика с различными фотосенсибилизаторами (ФД) [3].…”

Section: Introductionunclassified

Photodynamic therapy of penile leukoplakia: a case report

Shanazarov¹,

Kassymov²,

Muratov³

et al. 2022

Lazernaâ medicina

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Purpose: to describe a clinical case of successful application of photodynamic therapy (PDT) in a patient with leukoplakia of the glans penis skin.Material and methods. For PDT, chlorin-type photosensitizer “Photolon” was used. The photosensitizer (lyophilized powder) was diluted in 200.0 ml of 0.9 % sodium chloride solution, administered intravenously at dosage 1.5 mg/kg of body weight. After 2.5 hours, intravenous laser blood irradiation was performed with “Lakhta-Milon” laser device (output power – 100 mW, exposure – 30 minutes). Before PDT, ﬂuorescence diagnostics in ultraviolet light with wavelength 395–405 nm was performed. PDT technique was single-ﬁeld irradiation with output power 1800 mW (1.8 W), irradiation energy density – 150 J/cm2. Power density of laser light was 200 mW/cm2. Exposure time – 14 min.Results. After treatment, complete regression of the pathological focus and regeneration of healthy tissue were marked (one month).Conclusion. PDT in a patient with leukoplakia of glans penis is an effective and safe curative technique.

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Section: Introductionunclassified