Fluorescence based fiber optic and planar waveguide biosensors. A review

Benito‐Peña, Elena; Valdés, Mayra Granda; Glahn-Martínez, Bettina; Moreno‐Bondi, María C.

doi:10.1016/j.aca.2016.08.049

Cited by 94 publications

(55 citation statements)

References 195 publications

(142 reference statements)

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“…The optical sensor can detect fluorescence or the RI changes upon sensing the element target interaction. Currently, there are two methods to achieve a high sensitivity and resolution in terms of the RI sensing, the fiber, and sensitive surface plasmon resonance (SPR) techniques …”

Section: Graphene Assemblies For Biosensorsmentioning

confidence: 99%

Recent Advances in Sensing Applications of Graphene Assemblies and Their Composites

Tùng

Nine

Krebsz

et al. 2017

Adv Funct Materials

228

139

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Development of next-generation sensor devices is gaining tremendous attention in both academia and industry because of their broad applications in manufacturing processes, food and environment control, medicine, disease diagnostics, security and defense, aerospace, and so forth. Current challenges include the development of low-cost, ultrahigh, and user-friendly sensors, which have high selectivity, fast response and recovery times, and small dimensions. The critical demands of these new sensors are typically associated with advanced nanoscale sensing materials. Among them, graphene and its derivatives have demonstrated the ideal properties to overcome these challenges and have merged as one of the most popular sensing platforms for diverse applications. A broad range of graphene assemblies with different architectures, morphologies, and scales (from nano-, micro-, to macrosize) have been explored in recent years for designing new high-performing sensing devices. Herein, this study presents and discusses recent advances in synthesis strategies of assembled graphene-based superstructures of 1D, 2D, and 3D macroscopic shapes in the forms of fibers, thin films, and foams/aerogels. The fabricated state-of-the-art applications of these materials in gas and vapor, biomedical, piezoresistive strain and pressure, heavy metal ion, and temperature sensors are also systematically reviewed and discussed, and their sensing performance is compared.

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Section: Graphene Assemblies For Biosensorsmentioning

confidence: 99%

Recent Advances in Sensing Applications of Graphene Assemblies and Their Composites

Tùng

Nine

Krebsz

et al. 2017

Adv Funct Materials

228

139

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“…Biosensors are a potential alternative to classical methodologies for direct, reproducible, real-time and cheap detection of food allergens. Sensors are defined as integrated receptor-transducer devices which provide specific quantitative or semi-quantitative analytical information on the species of interest [ 43 ]. Biosensors contain a biological recognition element (biochemical receptor) in direct spatial contact with a transducer, which converts the recognition event into a measurable chemical or physical signal, connected to data acquisition and processing system [ 27 , 43 ].…”

Section: Current Analytical Methods For the Analysis Of Food Allermentioning

confidence: 99%

“…Several immunoassays based on the use of PMNMs and colorimetric detection have been reported for the rapid detection with simple operation, low cost, visual results and high sensitivity to allergens in food [ 43 , 84 ]. In most cases, they are based on lateral flow biosensors (LFBs) which are easy-to-use devices combining the advantages of lateral flow devices (LFA) such as portability, low-cost and rapidity, with the specificity and selectivity of immunoassays [ 85 , 86 ].…”

Section: Applications Of Nps In Bioassays and Biosensors For Food mentioning

confidence: 99%

“…Fluorescence is one of the most popular detection methods used in biosensing. Several parameters can be determined for sensing purposes including light intensity, decay time, or emission anisotropy [ 43 , 94 ]. This technique is especially suitable when meagre detection limits are essential and nowadays fluorescence transduction can be implemented using relatively simple schemes without the need of sophisticated instrumentation [ 95 ].…”

Section: Applications Of Nps In Bioassays and Biosensors For Food mentioning

confidence: 99%

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Biosensing Based on Nanoparticles for Food Allergens Detection

Gómez-Arribas

Benito‐Peña

Hurtado-Sánchez

et al. 2018

Sensors

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Food allergy is one of the major health threats for sensitized individuals all over the world and, over the years, the food industry has made significant efforts and investments to offer safe foods for allergic consumers. The analysis of the concentration of food allergen residues in processing equipment, in raw materials or in the final product, provides analytical information that can be used for risk assessment as well as to ensure that food-allergic consumers get accurate and useful information to make their food choices and purchasing decisions. The development of biosensors based on nanomaterials for applications in food analysis is a challenging area of growing interest in the last years. Research in this field requires the combined efforts of experts in very different areas including food chemistry, biotechnology or materials science. However, the outcome of such collaboration can be of significant impact on the food industry as well as for consumer’s safety. These nanobiosensing devices allow the rapid, selective, sensitive, cost-effective and, in some cases, in-field, online and real-time detection of a wide range of compounds, even in complex matrices. Moreover, they can also enable the design of novel allergen detection strategies. Herein we review the main advances in the use of nanoparticles for the development of biosensors and bioassays for allergen detection, in food samples, over the past few years. Research in this area is still in its infancy in comparison, for instance, to the application of nanobiosensors for clinical analysis. However, it will be of interest for the development of new technologies that reduce the gap between laboratory research and industrial applications.

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“…Planar optical waveguide (POWG) sensing platforms are well known, highly sensitive, small sized, immune to electromagnetic interference, enabling room temperature monitoring, and have been used to measure various measurands including DNA, trace acidic gases, and VOCs . The basic operational principle of POWG is to measure the changes in the refractive index or the absorbance that occurs close to the surface of the sensing film .…”

Section: Introductionmentioning

confidence: 99%

Preparation and Optical Study of Zn(II) Metal Organic Framework Thin Film for Xylene Gas Sensing Application

Tuergong

Nizamidin

Yin

et al. 2019

Physica Status Solidi (a)

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An optically transparent metal‐organic framework thin film, [Zn2(bdc)2(dpNDI)]n, is grown on the tin‐diffused glass substrate using layer‐by‐layer liquid phase epitaxial (LPE) growth method at room temperature (20 °C). The influence of growth cycle on morphology, optical properties, and gas sensibility of [Zn2(bdc)2(dpNDI)]n thin film is studied for the first time. The [Zn2(bdc)2(dpNDI)]n thin film displays a honeycomb framework with a large pore size, uniform surface morphology, and higher absorbance after 11 cycles of growth. The optical gas sensing performance of [Zn2(bdc)2(dpNDI)]n thin films is then monitored using the planar optical waveguide (POWG) gas detection system under UV light (395 nm) irradiation. As a result, the [Zn2(bdc)2(dpNDI)]n thin film POWGs exhibit a greater adsorption response to xylene gas, due to the larger refractive index and absorbance changes upon various volatile organic compounds (VOCs). The thin film POWG sensor shows fast, reversible response to xylene gas, in the concentration range of 1–1000 ppm. Furthermore, the xylene gas adsorption kinetics at different temperature is also investigated, in which the xylene gas adsorption behaviors of [Zn2(bdc)2(dpNDI)]n thin film follow a pseudo‐second order (PSO) model; at room temperature, the adsorption capacity on the unit surface is 7.92 μg cm−2.

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Fluorescence based fiber optic and planar waveguide biosensors. A review

Cited by 94 publications

References 195 publications

Recent Advances in Sensing Applications of Graphene Assemblies and Their Composites

Recent Advances in Sensing Applications of Graphene Assemblies and Their Composites

Biosensing Based on Nanoparticles for Food Allergens Detection

Preparation and Optical Study of Zn(II) Metal Organic Framework Thin Film for Xylene Gas Sensing Application

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