Flow-injection chemiluminescence determination of fluoroquinolones by enhancement of weak chemiluminescence from peroxynitrous acid

Flow-Injection Chemiluminescence Determination of Ofloxacin and Levofloxacin in Pharmaceutical Preparations and Biological Fluids

“…The proposed CL method used cheaper instruments and reagents than those of spectrophotometry, fluorometry, HPLC and other CL method with terbium(III) and europium(III) as enhancers. As compared with other CL methods described in the literature, [14][15][16][17][18][19] the proposed method has higher sensitivity. The proposed flowinjection CL method can be used for routine determination of OFLX and LOFLX in pharmaceutical preparations and biological fluids.…”

“…17 The use of hydrogen peroxide as oxidant for sodium nitrite-sulfuric acid system was described for the determination of ciprofloxacin, norfloxacin and ofloxacin in pharmaceutical preparations by enhancement of weak CL from peroxynitrous acid with a detection limit of 1.1 × 10 -7 mol l -1 ofloxacin. 18 But the CL method for the determinations of LOFLX has seldom been reported. An Eu(III) sensitized CL-Ce(IV)-sulfite system has been applied for determination of levofloxacin, moxifloxacin and trovafloxacin in pharmaceutical preparations with a detection limit of 0.100 mg ml -1 for LOFLX.…”

Determination of norfloxacin using a terbium‐sensitized electrogenerated chemiluminescence method

“…), including the chemiluminescence method. However, its reproducibility is not as good as the flow-injection chemiluminescence method (21). The mechanism of ECL in this system has been proposed.…”

Study on the chemiluminescence resonance energy transfer between luminol and fluorescent dyes using a linear CCD spectrometer

“…Based on flow-injection sampling technique, flow-injection CL analysis has been known as a rapid, sensitive, simple analytical method and has been widely used [2][3][4][5][6]. Luminol-metal ion is a classic CL system [1,7,8], and some CL analytical methods are known to be based on the catalysis of the oxidization of luminol with metal ions being used as catalysts [9][10][11].…”